Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by
the conversion of immunoglobulin light chains from their soluble functional states into highly …

The amyloidoses are a group of systemic diseases characterized by organ deposition of
misfolded protein fragments of diverse origins. The natural history of the disease …

Amyloid light chain (AL) amyloidosis is a rare, debilitating, often fatal disease. Symptoms of
cardiomyopathy are common presenting features, and patients often are referred to …

Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to
produce the amyloidogenic light chains. They are able to misfold and aggregate, deposit in …

Immunoglobulin light chain amyloidosis (AL) should be considered in any patient that
presents to a cancer care provider with nephrotic range proteinuria, heart failure with …

Immunoglobulin light chain amyloidosis (AL) commonly presents with nephrotic range
proteinuria, heart failure with preserved ejection fraction, nondiabetic peripheral neuropathy …

Opinion statement Cardiac amyloidosis is associated with a high mortality rate, a long delay
between the first signs and the diagnosis but a short interval between diagnosis and death …

As a growing number of patients with multiple myeloma (MM) respond to upfront therapies
while eventually relapsing in a time frame that is often unpredictable, attention has …

Introduction Systemic amyloidosis is a progressive disorder characterized by the
extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and …

Amyloidosis constitutes a large spectrum of diseases characterized by an extracellular
deposition of a fibrillar aggregate, generating insoluble and toxic amasses that may be …