Polymers with spatial or topological constraints: Theoretical and computational results

C Micheletti, D Marenduzzo, E Orlandini - Physics Reports, 2011 - Elsevier
In this review, we provide an organized summary of the theoretical and computational
results that are available for polymers subject to spatial or topological constraints. Because …

DNA curvature and flexibility in vitro and in vivo

JP Peters, LJ Maher - Quarterly reviews of biophysics, 2010 - cambridge.org
It has been more than 50 years since the elucidation of the structure of double-helical DNA.
Despite active research and progress in DNA biology and biochemistry, much remains to be …

FiberApp: an open-source software for tracking and analyzing polymers, filaments, biomacromolecules, and fibrous objects

I Usov, R Mezzenga - Macromolecules, 2015 - ACS Publications
Biological semiflexible polymers and filaments such as collagen, fibronectin, actin,
microtubules, coiled-coil proteins, DNA, siRNA, amyloid fibrils, etc., are ubiquitous in nature …

Understanding amyloid aggregation by statistical analysis of atomic force microscopy images

J Adamcik, JM Jung, J Flakowski, P De Los Rios… - Nature …, 2010 - nature.com
The aggregation of proteins is central to many aspects of daily life, including food
processing, blood coagulation, eye cataract formation disease and prion-related …

[HTML][HTML] CENP-B-mediated DNA loops regulate activity and stability of human centromeres

F Chardon, A Japaridze, H Witt, L Velikovsky… - Molecular cell, 2022 - cell.com
Chromosome inheritance depends on centromeres, epigenetically specified regions of
chromosomes. While conventional human centromeres are known to be built of long tandem …

Proteins fibrils from a polymer physics perspective

J Adamcik, R Mezzenga - Macromolecules, 2012 - ACS Publications
Protein fibrils resulting from assembly of proteins or peptides into long, insoluble, highly
ordered fibrillar structures are emerging as one of the fastest growing scientific areas, since …

Single-molecule structure and topology of kinetoplast DNA networks

P He, AJ Katan, L Tubiana, C Dekker, D Michieletto - Physical Review X, 2023 - APS
Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked
DNA minicircles found in certain parasites called trypanosomes. Understanding the self …

Persistence length and scaling properties of single-stranded DNA adsorbed on modified graphite

K Rechendorff, G Witz, J Adamcik… - The Journal of chemical …, 2009 - pubs.aip.org
We have characterized the polymer physics of single-stranded DNA (ssDNA) using atomic
force microscopy. The persistence length ℓ p of circular ssDNA adsorbed on a modified …

Knotting and metric scaling properties of DNA confined in nano-channels: a Monte Carlo study

C Micheletti, E Orlandini - Soft Matter, 2012 - pubs.rsc.org
We report on a numerical study of the equilibrium metric scaling features and knotting
properties of linear and circular model DNA chains inside cylindrical channels. The model …

Numerical study of linear and circular model DNA chains confined in a slit: metric and topological properties

C Micheletti, E Orlandini - Macromolecules, 2012 - ACS Publications
Advanced Monte Carlo simulations are used to study the effect of nanoslit confinement on
metric and topological properties of model DNA chains. We consider both linear and …