Pathological changes of brain oscillations following ischemic stroke

Y Sato, O Schmitt, Z Ip, G Rabiller… - Journal of Cerebral …, 2022 - journals.sagepub.com
Brain oscillations recorded in the extracellular space are among the most important aspects
of neurophysiology data reflecting the activity and function of neurons in a population or a …

Large-scale multimodal surface neural interfaces for primates

T Belloir, S Montalvo-Vargo, Z Ahmed, DJ Griggs… - iScience, 2023 - cell.com
Deciphering the function of neural circuits can help with the understanding of brain function
and treating neurological disorders. Progress toward this goal relies on the development of …

A versatile toolbox for studying cortical physiology in primates

K Khateeb, J Bloch, J Zhou, M Rahimi, DJ Griggs… - Cell reports …, 2022 - cell.com
Lesioning and neurophysiological studies have facilitated the elucidation of cortical
functions and mechanisms of functional recovery following injury. Clinical translation of such …

Polymer Skulls With Integrated Transparent Electrode Arrays for Cortex‐Wide Opto‐Electrophysiological Recordings

PD Donaldson, ZS Navabi, RE Carter… - Advanced …, 2022 - Wiley Online Library
Electrophysiology and optical imaging provide complementary neural sensing capabilities–
electrophysiological recordings have high temporal resolution, while optical imaging allows …

Improving the efficacy and accessibility of intracranial viral vector delivery in non-human primates

DJ Griggs, AD Garcia, WY Au, WKS Ojemann… - Pharmaceutics, 2022 - mdpi.com
Non-human primates (NHPs) are precious resources for cutting-edge neuroscientific
research, including large-scale viral vector-based experimentation such as optogenetics …

[HTML][HTML] Protocol to study ischemic stroke by photothrombotic lesioning in the cortex of non-human primates

N Stanis, K Khateeb, J Zhou, RK Wang… - STAR protocols, 2023 - Elsevier
Neurorehabilitation strategies for ischemic stroke have shown promise for functional
recovery, yet minimal tools are available to study rehabilitation techniques in non-human …

Neuroprotective effects of electrical stimulation following ischemic stroke in non-human primates

J Zhou, K Khateeb, A Gala, M Rahimi… - 2022 44th Annual …, 2022 - ieeexplore.ieee.org
Brain stimulation has emerged as a novel therapy for ischemic stroke, a major cause of brain
injury that often results in lifelong disability. Although past works in rodents have …

Demonstration of an optimized large-scale optogenetic cortical interface for non-human primates

DJ Griggs, J Bloch, S Fisher… - 2022 44th Annual …, 2022 - ieeexplore.ieee.org
Optogenetics is a powerful neuroscientific tool which allows neurons to be modulated by
optical stimulation. Despite widespread optogenetic experimentation in small animal …

Large-scale neural interfaces for optogenetic actuators and sensors in non-human primates

DJ Griggs, T Belloir… - Integrated Sensors for …, 2021 - spiedigitallibrary.org
Optogenetics is a powerful tool for relating brain function to behavior, as it enables cell-type
specific manipulation and recording of neurons with high spatial and temporal precision …

Convection Enhanced Delivery of Viral Vectors

D Griggs, T Belloir, J Zhou… - … for Optogenetics and …, 2023 - Springer
Convection-enhanced delivery (CED) is a pressure-based approach of delivering agents,
such as viral vectors, throughout large regions of tissue. CED is chiefly characterized by …