Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

The prevalence of hypovitaminosis D has risen in developed countries over the past few
years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D …

Background Vitamin D status has been implicated in COVID-19 disease. The objective of the
COVID-VIT-D trial was to investigate if an oral bolus of cholecalciferol (100,000 IU) …

Vitamin D is a steroid hormone with potent immune-modulating properties. It has been
shown to stimulate innate immunity and induce immune tolerance. Extensive research …

Aromatase inhibitors (AIs) have radically changed the prognosis of hormone receptor
positive breast cancer (BC) in post-menopausal women, and are a mainstay of the adjuvant …

The renal actions of parathyroid hormone (PTH) promote 1, 25-vitamin D generation;
however, the signaling mechanisms that control PTH-dependent vitamin D activation remain …

Vitamin D is one significant prohormone substance in human organ systems. It is a steroidal
hormone produced in the skin upon exposure to UVB rays. This paper presents a systematic …

Since its discovery, vitamin D was shown to have both immunostimulatory and
immunomodulatory effects on the immune system. A growing body of evidence so far linked …

The role of gut microbiota on immune regulation and the development of autoimmune
diseases such as rheumatoid arthritis (RA) is an emerging research topic. Multiple studies …

Antioxidant mechanisms are constituted of enzymes, endogenous, and non-enzymatic,
exogenous, which have the role of counterbalancing oxidative stress. Intake of these …