In light of the frequency, morbidity and mortality associated with influenza-associated
aspergillosis in the ICU, a high awareness of the diagnosis and prompt initiation of …

The world had been anticipating another influenza pandemic since the last one in 1968. The
pandemic influenza A H1N1 2009 virus (A/2009/H1N1) finally arrived, causing the first …

COVID-19 pathogenesis is associated with an exaggerated immune response. However, the
specific cellular mediators and inflammatory components driving diverse clinical disease …

Although several dozen studies of gene expression in sepsis have been published,
distinguishing sepsis from a sterile systemic inflammatory response syndrome (SIRS) is still …

Improved risk stratification and prognosis prediction in sepsis is a critical unmet need.
Clinical severity scores and available assays such as blood lactate reflect global illness …

Improved diagnostics for acute infections could decrease morbidity and mortality by
increasing early antibiotics for patients with bacterial infections and reducing unnecessary …

Given the manifold ways that depression impairs Darwinian fitness, the persistence in the
human genome of risk alleles for the disorder remains a much debated mystery …

Respiratory viral infections are a significant burden to healthcare worldwide. Many whole
genome expression profiles have identified different respiratory viral infection signatures, but …

Improved identification of bacterial and viral infections would reduce morbidity from sepsis,
reduce antibiotic overuse, and lower healthcare costs. Here, we develop a generalizable …

While most respiratory viral infections resolve with little harm to the host, severe symptoms
arise when infection triggers an aberrant inflammatory response that damages lung tissue …