Acute myeloid leukemia (AML) is a kind of malignant hematopoietic system disease
characterized by abnormal proliferation, poor cell differentiation, and infiltration of bone …

Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

The development of multidrug resistance (MDR) to chemotherapy remains a major
challenge in the treatment of cancer. Resistance exists against every effective anticancer …

Acute myeloid leukemia (AML) is characterized by an increase in the number of myeloid
cells in the marrow and an arrest in their maturation, frequently resulting in hematopoietic …

This review presents the latest data on the importance of selenium nanoparticles in human
health, their use in medicine, and the main known methods of their production by various …

Multidrug-resistant cancer cells frequently overexpress the 110-kD LRP protein (originally
named Lung Resistance-related Protein). LRP overexpression has been found to predict a …

Multixenobiotic resistance in aquatic organisms exposed to natural toxins or anthropogenic
contaminants is a phenomenon analogous to multidrug resistance in mammalian tumor cell …

Background: External beam radiotherapy is standard treatment for medium and large, or
visually threatening, intraocular retinoblastoma but markedly increases the risk of cosmetic …

Mammalian vaults are ribonucleoprotein (RNP) complexes, composed of a small ribonucleic
acid and three proteins of 100, 193, and 240 kD in size. The 100-kD major vault protein …

Zosuquidar, which modulates P-glycoprotein (P-gp) with minimal delay of anthracycline
clearance, may reverse P-gp–mediated resistance in acute myeloid leukemia without …