[HTML][HTML] First-and second-line systemic treatment of acute graft-versus-host disease: recommendations of the American Society of Blood and Marrow Transplantation

PJ Martin, JD Rizzo, JR Wingard, K Ballen… - Biology of Blood and …, 2012 - Elsevier
Despite prophylaxis with immunosuppressive agents or a variety of other approaches, many
patients suffer from acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic …

New and emerging therapies for acute and chronic graft versus host disease

LQ Hill, A Alousi, P Kebriaei, R Mehta… - Therapeutic …, 2018 - journals.sagepub.com
Graft versus host disease (GVHD) remains a major cause of morbidity and mortality
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey

R Zeiser, A Burchert, C Lengerke, M Verbeek… - Leukemia, 2015 - nature.com
Despite major improvements in allogeneic hematopoietic cell transplantation over the past
decades, corticosteroid-refractory (SR) acute (a) and chronic (c) graft-versus-host disease …

[HTML][HTML] Consensus conference on clinical practice in chronic GVHD: second-line treatment of chronic graft-versus-host disease

D Wolff, M Schleuning, S von Harsdorf, U Bacher… - Biology of Blood and …, 2011 - Elsevier
Steroid refractory chronic graft-versus-host disease (cGVHD) is associated with a significant
morbidity and mortality. Although first-line treatment of cGVHD is based on controlled trials …

Mesenchymal stem cell as salvage treatment for refractory chronic GVHD

JY Weng, X Du, SX Geng, YW Peng, Z Wang… - Bone marrow …, 2010 - nature.com
Refractory chronic GVHD (cGVHD) is an important complication after allogeneic
hematopoietic SCT and is prognostic of poor outcome. MSCs are involved in tissue repair …

Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease

B Fang, Y Song, L Liao, Y Zhang, RC Zhao - Transplantation proceedings, 2007 - Elsevier
There is no consistently effective therapy for patients with steroid-refractory acute graft-
versus-host disease (GVHD). Various alternative approaches have been tested, including …

Imatinib for refractory chronic graft-versus-host disease with fibrotic features

A Olivieri, F Locatelli, M Zecca, A Sanna… - Blood, The Journal …, 2009 - ashpublications.org
We previously reported that patients with fibrotic, chronic graft-versus-host disease (cGVHD)
have antibodies activating the platelet-derived growth factor receptor pathway. Because this …

Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow …

AM Alousi, DJ Weisdorf, BR Logan… - Blood, The Journal …, 2009 - ashpublications.org
Acute graft-versus-host disease (aGVHD) is the primary limitation of allogeneic
hematopoietic cell transplantation. Corticosteroids remain the standard initial therapy, yet …

Basiliximab for steroid‐refractory acute graft‐versus‐host disease: a real‐world analysis

XD Mo, SD Hong, YL Zhao, EL Jiang… - American journal of …, 2022 - Wiley Online Library
Steroid‐refractory (SR) acute graft‐versus‐host disease (aGVHD) is one of the leading
causes of early mortality after allogeneic hematopoietic stem cell transplantation (allo …

Evaluation of mycophenolate mofetil for initial treatment of chronic graft-versus-host disease

PJ Martin, BE Storer, SD Rowley… - Blood, The Journal …, 2009 - ashpublications.org
We conducted a double-blind, randomized multicenter trial to determine whether the
addition of mycophenolate mofetil (MMF) improves the efficacy of initial systemic treatment of …