The role of extracellular vesicles in cancer
R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
Chemical design of activatable photoacoustic probes for precise biomedical applications
Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …
integrates the advantage of optical and acoustic imaging, has great application prospects in …
Hydrogen-bonded organic framework-based bioorthogonal catalysis prevents drug metabolic inactivation
Bioorthogonal chemistry provides a new avenue for disease treatment by generating
therapeutic agents in situ. However, two crucial issues have to be considered for future …
therapeutic agents in situ. However, two crucial issues have to be considered for future …
Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Engineered extracellular vesicles for cancer therapy
X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment
S Wang, F Li, T Ye, J Wang, C Lyu, S Qing… - Science translational …, 2021 - science.org
Despite multiple immunotherapeutic technologies that achieve potent T cell activation,
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …
Bioorthogonal catalytic patch
Bioorthogonal catalysis mediated by transition metals has inspired a new subfield of artificial
chemistry complementary to enzymatic reactions, enabling the selective labelling of …
chemistry complementary to enzymatic reactions, enabling the selective labelling of …
Cancer‐cell‐Activated in situ synthesis of mitochondria‐targeting AIE photosensitizer for precise photodynamic therapy
Maximization of phototoxic damage on tumor with minimized side effect on normal tissue is
essential for effective anticancer photodynamic therapy (PDT). This requires highly cancer …
essential for effective anticancer photodynamic therapy (PDT). This requires highly cancer …