The immunology of successful pregnancy

AL Veenstra van Nieuwenhoven… - Human reproduction …, 2003 - academic.oup.com
Immune responses play an important role in various reproductive processes, including
ovulation, menstruation and parturition. Clearly, during pregnancy, when the mother must …

The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy

SL Straszewski-Chavez, VM Abrahams… - Endocrine …, 2005 - academic.oup.com
Apoptosis is important for normal placental development, but it may also be involved in the
pathophysiology of pregnancy-related diseases. Normal placental development is …

Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation

N Ishihara, H Matsuo, H Murakoshi… - American journal of …, 2002 - Elsevier
Objective: This study was undertaken to determine whether preeclampsia and intrauterine
growth retardation are associated with an increase in placental apoptosis. Study Design …

[HTML][HTML] Immunogenicity of human amniotic membrane in experimental xenotransplantation

M Kubo, Y Sonoda, R Muramatsu… - … ophthalmology & visual …, 2001 - tvst.arvojournals.org
purpose. The immunogenic characterization of amniotic membrane is still unknown. This
study was designed to examine the immunogenicity of human amniotic membrane, by using …

Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta

B Huppertz, HG Frank, JCP Kingdom, F Reister… - Histochemistry and cell …, 1998 - Springer
Villous trophoblast in the human placenta consists of a population of proliferating stem cells
which differentiate and individually fuse into the syncytiotrophoblast. We studied the …

Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts

N Hanna, I Hanna, M Hleb, E Wagner… - The Journal of …, 2000 - journals.aai.org
Control of antifetal immune responses is thought to be regulated locally by the placenta.
Because the physiologic programming of the placenta across gestation is likely to influence …

First trimester trophoblast cells secrete Fas ligand which induces immune cell apoptosis

VM Abrahams, SL Straszewski‐Chavez… - MHR: Basic science …, 2004 - academic.oup.com
Since the invading trophoblast represents a semi‐allograft, it should be rejected by the
mother. It has, therefore, been postulated that during normal pregnancy the trophoblast …

Stem cell characteristics and the therapeutic potential of amniotic epithelial cells

T Miki - American Journal of Reproductive Immunology, 2018 - Wiley Online Library
Multiple stem cell types can be isolated from the human placenta. Recent advances in stem
cell biology have revealed that human amniotic epithelial cells (hAEC s) are one of the …

TH1/TH2 paradigm in pregnancy: paradigm lost? Cytokines in pregnancy/early abortion: reexamining the TH1/TH2 paradigm

G Chaouat, N Ledée-Bataille, S Dubanchet… - International archives of …, 2004 - karger.com
In this paper, we briefly survey the history of concepts in reproductive immunology from
antibody-mediated tolerance to the 'fetal allograft'to the current concept of an embryo …

[HTML][HTML] Cellular and molecular regulation of spiral artery remodelling: lessons from the cardiovascular field

GSJ Whitley, JE Cartwright - Placenta, 2010 - Elsevier
A number of important changes take place in the maternal uterine vasculature during the first
few weeks of pregnancy resulting in increased blood flow to the intervillous space. Vascular …