[HTML][HTML] Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions

M Yan, Y Huo, S Yin, H Hu - Redox biology, 2018 - Elsevier
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure in
many developed countries. Mitochondrial oxidative stress is considered to be the …

The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

MAR Mia, D Dey, MR Sakib, MY Biswas… - Phytotherapy …, 2023 - Wiley Online Library
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy

EAR Abdelghffar, HAS El-Nashar, S Fayez… - Scientific Reports, 2022 - nature.com
Hepatic encephalopathy (HE) is a deterioration of brain function in patients suffering from
chronic liver disease, cirrhosis as a result of elevated blood ammonia and the production of …

Current insights into the biological action of squalene

JM Lou‐Bonafonte… - Molecular nutrition & …, 2018 - Wiley Online Library
Squalene is a triterpenic compound found in a large number of plants and other sources
with a long tradition of research since it was first reported in 1926. Herein a systematic …

Comparative Metabolic Study of Tamarindus indica L.'s Various Organs Based on GC/MS Analysis, In Silico and In Vitro Anti-Inflammatory and Wound Healing …

SH Aly, MA El-Hassab, SS Elhady, HA Gad - Plants, 2022 - mdpi.com
The chemical composition of the n-hexane extract of Tamarindus indica's various organs—
bark, leaves, seeds, and fruits (TIB, TIL, TIS, TIF)—was investigated using gas …

Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations

S Chilvery, A Yelne, A Khurana, MA Saifi, S Bansod… - Phytomedicine, 2023 - Elsevier
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

Comparative GC-MS analysis of fresh and dried Curcuma essential oils with insights into their antioxidant and enzyme inhibitory activities

NM Fahmy, S Fayez, AI Uba, MA Shariati… - Plants, 2023 - mdpi.com
Species belonging to the Zingiberaceae family are of high nutritional, industrial, and
medicinal values. In this study, we investigated the effect of processing steps (fresh vs. dried …

Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin‐Induced Organ Dysfunction in Rats: Comprehensive in vivo …

M Chandra Shill, HAS El‐Nashar… - Chemistry & …, 2024 - Wiley Online Library
This study focused to assess the efficacy of Gynura procumbens (GP) leaf extract against
cisplatin (CP)‐induced hepatorenal complications in Wister albino rats. Additionally, it aims …

Biological Characterization of Cleome felina Lf Extracts for Phytochemical, Antimicrobial, and Hepatoprotective Activities in Wister Albino Rats

HY Shaikh, SK Niazi, A Bepari, MAW Cordero… - Antibiotics, 2023 - mdpi.com
The present study aims to explore the phytochemical constitution and biological activities of
Cleome felina Lf (Cleomaceae). C. felina (leaves, stem, and root) extracts (acetone …

GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive …

C Sarkar, M Mondal, K Al-Khafaji, DM El-Kersh… - Life Sciences, 2022 - Elsevier
The present study attempted to scrutinize the protective effect of the methanolic extract of P.
chaba stem bark against paracetamol-induced hepatotoxicity in Sprague− Dawley rats …