Transthyretin (TTR) is a tetrameric protein synthesized primarily by the liver. TTR can misfold
into pathogenic ATTR amyloid fibrils that deposit in the nerves and heart, causing a …

Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate
evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium. TTR …

Cardiac involvement has a profound effect on the prognosis of patients with systemic
amyloidosis. Therapeutic methods for suppressing the production of causative proteins have …

Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver
and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other …

Transthyretin (TTR) is a tetrameric protein transporting hormones in the plasma and brain,
which has many other activities that have not been fully acknowledged. TTR is a positive …

Transthyretin (TTR) binds Aβ peptide, preventing its deposition and toxicity. TTR is
decreased in Alzheimer's disease (AD) patients. Additionally, AD transgenic mice with only …

Transthyretin (TTR), an homotetrameric protein mainly synthesized by the liver and the
choroid plexus, and secreted into the blood and the cerebrospinal fluid, respectively, has …

Transthyretin (TTR) amyloidoses are systemic diseases associated with TTR aggregation
and extracellular deposition in tissues as amyloid. The most frequent and severe forms of …

Transthyretin (TTR) is a protein that binds and distributes thyroid hormones (TH s). TTR
synthesised in the liver is secreted into the bloodstream and distributes TH s around the …

Transthyretin (TTR) is an extracellular protein mainly produced in the liver and choroid
plexus, with a well-stablished role in the transport of thyroxin and retinol throughout the body …