Molecular magnetic resonance imaging in cancer
The ability to identify key biomolecules and molecular changes associated with cancer
malignancy and the capacity to monitor the therapeutic outcome against these targets is …
malignancy and the capacity to monitor the therapeutic outcome against these targets is …
Advanced magnetic resonance imaging techniques in management of brain metastases
H Mehrabian, J Detsky, H Soliman, A Sahgal… - Frontiers in …, 2019 - frontiersin.org
Brain metastases are the most common intracranial tumors and occur in 20–40% of all
cancer patients. Lung cancer, breast cancer, and melanoma are the most frequent primary …
cancer patients. Lung cancer, breast cancer, and melanoma are the most frequent primary …
Relaxation-compensated CEST-MRI of the human brain at 7 T: unbiased insight into NOE and amide signal changes in human glioblastoma
Endogenous chemical exchange saturation transfer (CEST) effects of protons resonating
near to water protons are always diluted by competing effects such as direct water saturation …
near to water protons are always diluted by competing effects such as direct water saturation …
Downfield‐NOE‐suppressed amide‐CEST‐MRI at 7 Tesla provides a unique contrast in human glioblastoma
Purpose The chemical exchange saturation transfer (CEST) effect observed in brain tissue
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …
Molecular MRI differentiation between primary central nervous system lymphomas and high-grade gliomas using endogenous protein-based amide proton transfer …
Objectives To show the ability of using the amide proton transfer-weighted (APTW) MRI
signals as imaging biomarkers to differentiate primary central nervous system lymphomas …
signals as imaging biomarkers to differentiate primary central nervous system lymphomas …
Magnetic resonance imaging of glucose uptake and metabolism in patients with head and neck cancer
Imaging metabolic dysfunction, a hallmark of solid tumors, usually requires radioactive
tracers. Chemical exchange saturation transfer (CEST) imaging can potentially detect and …
tracers. Chemical exchange saturation transfer (CEST) imaging can potentially detect and …
State of the art MRI in head and neck cancer
YL Dai, AD King - Clinical radiology, 2018 - Elsevier
Head and neck cancer affects more than 11,000 new patients per year in the UK 1 and
imaging has an important role in the diagnosis, treatment planning, and assessment, and …
imaging has an important role in the diagnosis, treatment planning, and assessment, and …
Discriminating MGMT promoter methylation status in patients with glioblastoma employing amide proton transfer-weighted MRI metrics
Objectives To explore the feasibility of using amide proton transfer-weighted (APTw) MRI
metrics as surrogate biomarkers to identify the O6-methylguanine-DNA methyltransferase …
metrics as surrogate biomarkers to identify the O6-methylguanine-DNA methyltransferase …
Amide proton transfer CEST of the cervical spinal cord in multiple sclerosis patients at 3T
Purpose The ability to evaluate pathological changes in the spinal cord in multiple sclerosis
(MS) is limited because T1‐and T2‐w MRI imaging are not sensitive to biochemical changes …
(MS) is limited because T1‐and T2‐w MRI imaging are not sensitive to biochemical changes …
Head and neck tumors: amide proton transfer MRI
Purpose To evaluate the utility of amide proton transfer (APT) imaging in the characterization
of head and neck tumors. Materials and Methods This retrospective study of APT imaging …
of head and neck tumors. Materials and Methods This retrospective study of APT imaging …