Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …

The pentose phosphate pathway, one of the main antioxidant cellular defense systems, has
been related for a long time almost exclusively to its role as a provider of reducing power …

Metabolomics, one of the 'omic'sciences in systems biology, is the global assessment and
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …

Traditional Chinese medicine (TCM) is a holistic approach to health that attempts to bring
the body, mind and spirit into harmony. Entering 21st century, TCM is getting more and more …

Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be
associated with the etiology of cancer. Furthermore, accumulating evidence suggest that …

Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation
of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this …

The understanding that oncogenes can have profound effects on cellular metabolism and
the discovery of mutations and alterations in several metabolism-related enzymes …

It is well known that significant metabolic change take place as cells are transformed from
normal to malignant. This review focuses on the use of different bioinformatics tools in …

Aerobic metabolism occurs in a background of oxygen radicals and reactive oxygen species
(ROS) that originate from the incomplete reduction of molecular oxygen in electron transfer …

Cancer growth is predicted to require substantial rates of substrate catabolism and ATP
turnover to drive unrestricted biosynthesis and cell growth. While substrate limitation can …