5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Patterning of the vertebrate facial skeleton involves the progressive partitioning of neural-
crest-derived skeletal precursors into distinct subpopulations along the anteroposterior (AP) …

The gut contains a large 5-HT pool in enterochromaffin (EC) cells and a smaller 5-HT pool in
the enteric nervous system (ENS). During development, enteric neurons are generated …

Key points Xenopus laevis craniofacial development is a good system for the study of
Andersen–Tawil Syndrome (ATS)‐associated craniofacial anomalies (CFAs) because (1) …

Auriculocondylar syndrome (ACS) is a rare, autosomal-dominant craniofacial malformation
syndrome characterized by variable micrognathia, temporomandibular joint ankylosis, cleft …

ABSTRACT A key problem in evolutionary developmental biology is identifying the sources
of instructive information that determine species-specific anatomical pattern. Understanding …

During the development of the vertebrate feeding apparatus, a variety of complicated
cellular and molecular processes participate in the formation and integration of individual …

Since its discovery in 1937, serotonin (5-HT) has become one of the most studied biogenic
amines due to its predominant role in regulating several physiological processes such as …

The monoamine neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has important
functions both in the neural system and during embryonic development in mammals. In this …

Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions
in the nervous system. Serotonin receptors are also ubiquitously expressed in various …