A molecular understanding of alphavirus entry and antibody protection
AS Kim, MS Diamond - Nature Reviews Microbiology, 2023 - nature.com
Alphaviruses are arthropod-transmitted RNA viruses that cause epidemics of human
infection and disease on a global scale. These viruses are classified as either arthritogenic …
infection and disease on a global scale. These viruses are classified as either arthritogenic …
The viral class II membrane fusion machinery: divergent evolution from an ancestral heterodimer
P Guardado-Calvo, FA Rey - Viruses, 2021 - mdpi.com
A key step during the entry of enveloped viruses into cells is the merger of viral and cell lipid
bilayers. This process is driven by a dedicated membrane fusion protein (MFP) present at …
bilayers. This process is driven by a dedicated membrane fusion protein (MFP) present at …
Shifts in receptors during submergence of an encephalitic arbovirus
Western equine encephalitis virus (WEEV) is an arthropod-borne virus (arbovirus) that
frequently caused major outbreaks of encephalitis in humans and horses in the early …
frequently caused major outbreaks of encephalitis in humans and horses in the early …
Structure of Semliki Forest virus in complex with its receptor VLDLR
Semliki Forest virus (SFV) is an alphavirus that uses the very-low-density lipoprotein
receptor (VLDLR) as a receptor during infection of its vertebrate hosts and insect vectors …
receptor (VLDLR) as a receptor during infection of its vertebrate hosts and insect vectors …
The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses
Members of the low-density lipoprotein receptor (LDLR) family, including LDLRAD3, VLDLR,
and ApoER2, were recently described as entry factors for different alphaviruses. However …
and ApoER2, were recently described as entry factors for different alphaviruses. However …
The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes
Abstract Eastern Equine Encephalitis virus (EEEV) is an alphavirus that can cause severe
diseases in infected humans. The very low-density lipoprotein receptor (VLDLR) was …
diseases in infected humans. The very low-density lipoprotein receptor (VLDLR) was …
Structural basis for VLDLR recognition by eastern equine encephalitis virus
Eastern equine encephalitis virus (EEEV) is the most virulent alphavirus that infects humans,
and many survivors develop neurological sequelae, including paralysis and intellectual …
and many survivors develop neurological sequelae, including paralysis and intellectual …
Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice
Venezuelan equine encephalitis virus (VEEV) is an encephalitic alphavirus responsible for
epidemics of neurological disease across the Americas. Low-density lipoprotein receptor …
epidemics of neurological disease across the Americas. Low-density lipoprotein receptor …
The many ways in which alphaviruses bind to cells
S Raju, LJ Adams, MS Diamond - Trends in Immunology, 2024 - cell.com
Only a subset of viruses can productively infect many different host species. Some arthropod-
transmitted viruses, such as alphaviruses, can infect invertebrate and vertebrate species …
transmitted viruses, such as alphaviruses, can infect invertebrate and vertebrate species …
Structural basis of the recognition of adeno-associated virus by the neurological system-related receptor carbonic anhydrase IV
R Zhang, Y Liu, F Yu, G Xu, L Li, B Li, Z Lou - Plos Pathogens, 2024 - journals.plos.org
Carbonic anhydrase IV (Car4) is a newly identified receptor that allows adeno-associated
virus (AAV) 9P31 to cross the blood-brain barrier and achieve efficient infection in the central …
virus (AAV) 9P31 to cross the blood-brain barrier and achieve efficient infection in the central …