Regulatory T cells (Tregs) possess unique immunosuppressive activity among CD4-positive
T cells. Tregs are ubiquitously present in mammals and function to calm excessive immune …

Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue
homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility …

Interferon-inducible transmembrane (IFITM) family members (IFITM1, IFITM2, IFITM3) are
extensively expressed in T cells and are involved in adaptive immunity. However, little is …

Interferon-induced transmembrane proteins (IFITMs) are upregulated by interferons. They
are not only highly conserved in evolution but also structurally consistent and have almost …

Progranulin (PGRN) plays a critical role in bronchial asthma and the function of various
immune cells. However, the mechanisms by which PGRN influences B‐cell receptor (BCR) …

Innate immunity protein interferon induced transmembrane protein 3 (IFITM3) is a
transmembrane protein that has a wide array of functions, including in viral infections …

Background/Objectives: Cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC)
represent major primary liver cancers, affecting one of the most vital organs in the human …

Sepsis, a leading cause of mortality in intensive care units worldwide, lacks effective
treatments for advanced-stage sepsis. Therefore, understanding the underlying mechanisms …

Background Systemic lupus erythematosus is a clinically heterogeneous autoimmune
disease that lacks reliable diagnostic biomarkers. In our study, we aimed to identify a novel …

The synthesis, structure and thermal decomposition behaviour of unique mononuclear,
homoleptic [pipH] 3 [Cu (O 2 CH) 5](2)(pipH+= piperidinium) is discussed in which the …