Clinical impact of computational heart valve models

M Toma, S Singh-Gryzbon, E Frankini, Z Wei… - Materials, 2022 - mdpi.com
This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

M Bucelli, A Zingaro, PC Africa… - … journal for numerical …, 2023 - Wiley Online Library
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

[HTML][HTML] Impact of calcific aortic valve disease on valve mechanics

BJ Vogl, NR Niemi, LG Griffiths, MA Alkhouli… - … and modeling in …, 2022 - Springer
The aortic valve is a highly dynamic structure characterized by a transvalvular flow that is
unsteady, pulsatile, and characterized by episodes of forward and reverse flow patterns …

Effect of blood pressure levels on sinus hemodynamics in relation to calcification after bioprosthetic aortic valve replacement

B Vogl, A Sularz, S Lilly, VH Thourani… - Annals of biomedical …, 2024 - Springer
Coexisting hypertension and aortic stenosis are common. Some studies showed that
elevated blood pressures may be associated with progression of calcific aortic valve disease …

Kinetic and dynamic effects on degradation of von willebrand factor

CS Jhun, L Xu, C Siedlecki, CR Bartoli, E Yeager… - Asaio …, 2023 - journals.lww.com
The loss of high molecular weight multimers (HMWM) of von Willebrand factor (vWF) in
aortic stenosis (AS) and continuous-flow left ventricular assist devices (cf-LVADs) is believed …

Nature of aortic annulus: Influence of annulus dynamic on the aortic valve hemodynamics

A Hashemifard, N Fatouraee, M Nabaei - Computers in Biology and …, 2024 - Elsevier
Accurate imaging reports of the aortic valve indicate that the diameter of the aortic annulus
changes regularly during a cardiac cycle. Most of these studies aim to demonstrate the …

Obtaining Vortex Formation in Blood Flow by Particle Tracking: Echo-PV Methods and Computer Simulation

I Starodumov, S Sokolov, K Makhaeva, P Mikushin… - Inventions, 2023 - mdpi.com
Micrometer-sized particles are widely introduced as fluid flow markers in experimental
studies of convective flows. The tracks of such particles demonstrate a high contrast in the …

Patient-specific fluid–structure interaction simulation of the LAD-ITA bypass graft for moderate and severe stenosis: A doubt on the fractional flow reserve-based …

F Tajeddini, B Firoozabadi, HA Pakravan… - Biocybernetics and …, 2022 - Elsevier
Fractional flow reserve (FFR)-based decision improves the outcomes of percutaneous
coronary intervention (PCI) for some patients, while its effectiveness in improving the results …

Influence of Aortic Valve Stenosis and Wall Shear Stress on Platelets Function

P Bańka, M Wybraniec, T Bochenek, B Gruchlik… - Journal of Clinical …, 2023 - mdpi.com
Aortic valve stenosis (AS) is a common heart valve disease in the elderly population, and its
pathogenesis remains an interesting area of research. The degeneration of the aortic valve …

Energy loss index as a predictor of all‐cause mortality after transcatheter aortic valve replacement: a long‐term follow‐up

G Johal, V Jonnala, L Pourafkari, S Sedghi… - …, 2023 - Wiley Online Library
Background As transcatheter aortic valve replacement (TAVR) procedures become more
widely available, there is a growing need to monitor and evaluate postoperative outcomes …