Reengineering of the human pyruvate dehydrogenase complex: from disintegration to highly active agglomerates

J Guo, S Hezaveh, J Tatur, AP Zeng… - Biochemical …, 2017 - portlandpress.com
The pyruvate dehydrogenase complex (PDC) plays a central role in cellular metabolism and
regulation. As a metabolite-channeling multi-enzyme complex it acts as a complete …