Imagine that you volunteer for the clinical trial of an experimental drug. The only direct
benefit of participating is that you will receive up to $5,175. You must spend twenty nights …

Background Phase 1 trials are increasingly important in the molecularly driven era of
oncology, but few studies have examined phase 1 participation disparities. The authors of …

To prepare for potential human infection challenge studies (HICS) involving SARS-CoV-2,
we convened a multidisciplinary working group to address ethical questions regarding …

Background Increasing the diversity of research participants is an important focus of clinical
trials. However, little is known regarding who enrolls as healthy volunteers in Phase I clinical …

Abstract Human Infection Studies (HIS) have emerged as an important research approach
with the potential to fast track the global development of vaccines and treatments for …

This article explores the relationship between personal sacrifice and identity work within
conditions of profound structural insecurity. We develop the concept of sacrificial labour to …

Phase I healthy volunteer trials test the safety and tolerability of investigational
pharmaceuticals. In them, participants are exposed to study‐drug risks without the possibility …

In the US, research payments are technically taxable income. This article argues that tax
liability is a form of possible economic and legal risk of paid research participation. Findings …

Objective: This study is to ascertain any inconsistencies in the trend of co-occurrence by sex
of teenage health risk behavior patterns such as smoking, behaviors contributing to …

Purpose To describe the motivations, barriers, and sociodemographic characteristics of
healthy Chinese volunteers in phase I research and to demonstrate the factors influencing …