Comparative pathology of zoonotic orthopoxviruses
AL MacNeill - Pathogens, 2022 - mdpi.com
This review provides a brief history of the impacts that a human-specific Orthopoxvirus
(OPXV), Variola virus, had on mankind, recalls how critical vaccination was for the …
(OPXV), Variola virus, had on mankind, recalls how critical vaccination was for the …
Vaccinia virus natural infections in Brazil: the good, the bad, and the ugly
The orthopoxviruses (OPV) comprise several emerging viruses with great importance to
human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of …
human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of …
The Virulence of Different Vaccinia Virus Strains Is Directly Proportional to Their Ability To Downmodulate Specific Cell-Mediated Immune Compartments In Vivo
LFD de Freitas, RP Oliveira, MCG Miranda… - Journal of …, 2019 - Am Soc Microbiol
Vaccinia virus (VACV) is a notorious virus for a number of scientific reasons; however, most
of its notoriety comes from the fact that it was used as a vaccine against smallpox, being …
of its notoriety comes from the fact that it was used as a vaccine against smallpox, being …
Drug combinations proposed by machine learning on genes/proteins to improve the efficacy of Tecovirimat in the treatment of Monkeypox: A Systematic Review and …
ABSTRACT Background The World Health Organization (WHO) describes Monkeypox as a
viral zoonosis, or an animal-to-human virus transmission, with symptoms comparable to …
viral zoonosis, or an animal-to-human virus transmission, with symptoms comparable to …
[HTML][HTML] The Unique Immune Evasion Mechanisms of the Mpox Virus and Their Implication for Developing New Vaccines and Immunotherapies
D Fang, Y Liu, D Dou, B Su - Virologica Sinica, 2024 - Elsevier
Mpox is an infectious and contagious zoonotic disease caused by the mpox virus (MPXV),
which belongs to the genus Orthopoxvirus. Since 2022, MPXV has posed a significant threat …
which belongs to the genus Orthopoxvirus. Since 2022, MPXV has posed a significant threat …
Vaccinia Virus: Mechanisms Supporting Immune Evasion and Successful Long-Term Protective Immunity
J Hsu, S Kim, N Anandasabapathy - Viruses, 2024 - mdpi.com
Vaccinia virus is the most successful vaccine in human history and functions as a protective
vaccine against smallpox and monkeypox, highlighting the importance of ongoing research …
vaccine against smallpox and monkeypox, highlighting the importance of ongoing research …
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo
KL Lourenço, TL Leão, CO Queiroz… - Experimental …, 2023 - journals.sagepub.com
The replicative success of vaccinia virus (VACV) depends on its ability to subvert host
functions. Poxviruses multiplication and maturation are closely associated with the …
functions. Poxviruses multiplication and maturation are closely associated with the …
Primary human B cells at different differentiation and maturation stages exhibit distinct susceptibilities to vaccinia virus binding and infection
N Shepherd, J Lan, W Li, S Rane, Q Yu - Journal of Virology, 2019 - Am Soc Microbiol
Vaccinia virus (VACV), the prototypical member of the poxvirus family, was used as a live-
virus vaccine to eradicate smallpox worldwide and has recently received considerable …
virus vaccine to eradicate smallpox worldwide and has recently received considerable …
Zoonotic vaccinia virus strains belonging to different genetic clades exhibit immunomodulation abilities that are proportional to their virulence
KL Lourenço, LA Chinália, LR Henriques… - Virology journal, 2021 - Springer
Background The vaccinia virus (VACV) isolates, Guarani P1 virus (GP1V) and Passatempo
virus (PSTV), were isolated during zoonotic outbreaks in Brazil. Each one of them belongs to …
virus (PSTV), were isolated during zoonotic outbreaks in Brazil. Each one of them belongs to …
[HTML][HTML] CD4 and CD8 T cells participate in the immune memory response against Vaccinia virus after a previous natural infection
DC Medeiros-Silva, EA dos Santos Moreira-Silva… - Results in …, 2013 - Elsevier
The present study evaluates the immune response of memory CD4+ and CD8+ T cells from
patients following a natural Vaccinia virus (VACV) infection. A total of 42 individuals were …
patients following a natural Vaccinia virus (VACV) infection. A total of 42 individuals were …