NPM1/B23: a multifunctional chaperone in ribosome biogenesis and chromatin remodeling
MS Lindström - Biochemistry research international, 2011 - Wiley Online Library
At a first glance, ribosome biogenesis and chromatin remodeling are quite different
processes, but they share a common problem involving interactions between charged …
processes, but they share a common problem involving interactions between charged …
Fly fishing for histones: catch and release by histone chaperone intrinsically disordered regions and acidic stretches
C Warren, D Shechter - Journal of molecular biology, 2017 - Elsevier
Chromatin is the complex of eukaryotic DNA and proteins required for the efficient
compaction of the nearly 2-meter-long human genome into a roughly 10-micron-diameter …
compaction of the nearly 2-meter-long human genome into a roughly 10-micron-diameter …
Altered machinery of protein synthesis in Alzheimer's: from the nucleolus to the ribosome
K Hernández‐Ortega, P Garcia‐Esparcia, L Gil… - brain …, 2016 - Wiley Online Library
Ribosomes and protein synthesis have been reported to be altered in the cerebral cortex at
advanced stages of Alzheimer's disease (AD). Modifications in the hippocampus with …
advanced stages of Alzheimer's disease (AD). Modifications in the hippocampus with …
Function of homo-and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling
Sperm chromatin remodeling after oocyte entry is the essential step that initiates
embryogenesis. This reaction involves the removal of sperm-specific basic proteins and …
embryogenesis. This reaction involves the removal of sperm-specific basic proteins and …
Identification of novel adipokines through proteomic profiling of small extracellular vesicles derived from adipose tissue
Y Zhang, M Yu, J Dong, Y Wu… - Journal of proteome …, 2020 - ACS Publications
Adipose tissue is regarded as a true endocrine organ that releases adipokines to regulate
distant targets. Besides the well-studied secretory adipokines, the adipokines carried by …
distant targets. Besides the well-studied secretory adipokines, the adipokines carried by …
The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone
SS Gadad, P Senapati, SH Syed, RE Rajan… - Biochemistry, 2011 - ACS Publications
Linker histone H1 plays an essential role in chromatin organization. Proper deposition of
linker histone H1 as well as its removal is essential for chromatin dynamics and function …
linker histone H1 as well as its removal is essential for chromatin dynamics and function …
Fatal familial insomnia: mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus
MA Frau‐Méndez, I Fernández‐Vega… - Brain …, 2017 - Wiley Online Library
The expression of subunits of mitochondrial respiratory complexes and components of the
protein synthesis machinery from the nucleolus to the ribosome was analyzed in the …
protein synthesis machinery from the nucleolus to the ribosome was analyzed in the …
[HTML][HTML] SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A
The histone demethylase JMJD2A/KDM4A facilitates prostate cancer development, yet how
JMJD2A function is regulated has remained elusive. Here, we demonstrate that SET7/9 …
JMJD2A function is regulated has remained elusive. Here, we demonstrate that SET7/9 …
Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer
H Wang, Z Zhou, J Zhang, T Hao, P Wang, P Wu, R Su… - Cancer Letters, 2024 - Elsevier
Abnormal regulation of RNA binding proteins (RBPs) plays an essential role in
tumorigenesis and progression, but their functions and mechanisms remain largely elusive …
tumorigenesis and progression, but their functions and mechanisms remain largely elusive …
NPM3 as a novel oncogenic factor and poor prognostic marker contributes to cell proliferation and migration in lung adenocarcinoma
S Wei, J Xing, K Lu, K Wang, W Yu - Hereditas, 2023 - Springer
Background Lung cancer is the leading cause of cancer-related deaths worldwide, and
despite recent advances in targeted therapies and immunotherapies, the clinical benefit …
despite recent advances in targeted therapies and immunotherapies, the clinical benefit …