Supercritical Carbon Dioxide Technology for Recovering Valuable Phytochemicals from Cannabis sativa L. and Valorization of Its Biomass for Food Applications

AC de Aguiar, R Vardanega, J Viganó, EK Silva - Molecules, 2023 - mdpi.com
Supercritical carbon dioxide (CO2) extraction techniques meet all-new consumer market
demands for health-promoting phytochemical compound-rich extracts produced from green …

Investigation of retention behavior of natural cannabinoids on differently substituted polysaccharide-based chiral stationary phases under reversed-phase liquid …

C De Luca, A Buratti, W Umstead, P Franco… - … of Chromatography A, 2022 - Elsevier
The growing popularity of cannabis products and recent legalization of cannabis for
recreational purposes have contributed to the increase of the demand for analytical methods …

Chiral Separation of Cannabichromene, Cannabicyclol, and Their Acidic Analogs on Polysaccharide Chiral Stationary Phases

JM Ferraro, WJ Umstead - Molecules, 2023 - mdpi.com
Until recently, chirality has not been a major focus in the study of cannabinoids, as most
cannabinoids of interest, such as cannabidiol and tetrahydrocannabinol, exist as a single …

Progress in the analysis of phytocannabinoids by HPLC and UPLC (or UHPLC) during 2020–2023

L Nahar, P Chaiwut, S Sangthong… - Phytochemical …, 2024 - Wiley Online Library
Introduction Organic molecules that bind to cannabinoid receptors are known as
cannabinoids. These molecules possess pharmacological properties similar to those …

[HTML][HTML] Green cannabigerol purification through simulated moving bed chromatography

C De Luca, Y Krauke, S Stephan, G Greco… - Green Analytical …, 2023 - Elsevier
Cannabigerol (CBG) is a minor cannabinoid present in Cannabis sativa L. This molecule is
gaining increasing popularity thanks to its antibacterial, antimicrobial, antidepressant and …

Sequential purification of cannabidiol by two-dimensional liquid chromatography combined with modeling and simulation of elution profiles

MH Ardakani, H Rezadoost, HR Norouzi - Journal of Chromatography A, 2024 - Elsevier
Cannabidiol (CBD) has garnered significant attention for its neuroprotective properties, and
research on its therapeutic effects has increased dramatically in recent years. However, the …

[HTML][HTML] Enantioseparation of chiral phytocannabinoids in medicinal cannabis

F Russo, F Tolomeo, MA Vandelli, G Biagini… - … of Chromatography B, 2023 - Elsevier
The evaluation of the chiral composition of phytocannabinoids in the cannabis plant is
particularly important as the pharmacological effects of the (+) and (-) enantiomers of these …

Liquid electron ionization-mass spectrometry as a novel strategy for integrating normal-phase liquid chromatography with low and high-resolution mass spectrometry

N Marittimo, G Grasselli, A Arigò, G Famiglini… - Analyst, 2024 - pubs.rsc.org
Normal-phase liquid chromatography (NPLC) plays a pivotal role in the rapid separation of
non-polar compounds, facilitating isomer separation and finding applications in various …

Kamlet-Taft parameters of solvents and their relationship with methylation of hydroxy group by Ag2O

M Aryafard, J Nisler - Journal of Molecular Liquids, 2024 - Elsevier
We measured the effects of Kamlet-Taft parameters on methylation of hydroxy group of N-(2-
hydroxyethyl) phthalimide by Ag 2 O. Optimization of methylation was done by tuning the …

Sustainable cannabinoids purification through twin-column recycling chromatography and green solvents

G Compagnin, C De Luca, C Nosengo… - Analytical and …, 2024 - Springer
In the present study, twin-column recycling chromatography has been employed for the
purification of a Cannabis extract by using a green solvent, ethanol, as the mobile phase. In …