Tumour progression is dependent on the interaction between tumour cells and cells of the
surrounding microenvironment. The tumour is a dynamic milieu consisting of various cell …

In adult mammals, hematopoietic stem cells (HSCs) are defined by their abilities to self‐
renew and to differentiate to form all blood cell lineages. These rare multipotent cells occupy …

The term osteoimmunology was coined many years ago to describe the research field that
deals with the cross-regulation between bone cells and the immune system. As a matter of …

Haematopoietic stem cells (HSCs) are multipotent, self-renewing progenitors that generate
all mature blood cells. HSC function is tightly controlled to maintain haematopoietic …

The concept of hematopoietic stem cell (HSC) niche was formulated in 1978, but HSC
niches remained unidentified for the following two decades largely owing to technical …

Enhancement of hematopoietic recovery after radiation, chemotherapy, or hematopoietic
stem cell (HSC) transplantation is clinically relevant. Dipeptidylpeptidase (DPP4) cleaves a …

Pancytopenia is a major cause of morbidity in acute myeloid leukemia (AML), yet its cause is
unclear. Normal osteoblastic cells have been shown to support hematopoiesis. To define the …

Here, we propose a collagen-based three-dimensional (3D) environment for hematopoietic
stem and progenitor cells (HPC) with mesenchymal stem cells (MSC) derived either from …

Obesity markedly increases susceptibility to a range of diseases and simultaneously
undermines the viability and fate selection of haematopoietic stem cells (HSCs), and thus …

Tumor microenvironment represents the site where the tumor tries to survive and escape
from immune system-mediated recognition. Indeed, to proliferate tumor cells can divert the …