Cardiovascular diseases caused by atherosclerosis do not typically manifest before middle
age; however, the disease process begins early in life. Preclinical atherosclerosis can be …

Cardiometabolic diseases contribute more to global morbidity and mortality than any other
group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually …

Childhood obesity has been increasing steadily in recent decades, and severe childhood
obesity has emerged as a major public health problem both nationally and internationally. A …

Importance Cardiometabolic disorders often occur concomitantly with psychosis and
depression, contribute to high mortality rates, and are detectable from the onset of the …

Background: Cardiovascular risk factors, such as high blood pressure, adverse serum lipids,
and elevated body mass index in midlife, may harm cognitive performance. It is important to …

Importance Childhood lipid levels have been associated with adult subclinical
atherosclerosis; however, life-course lipid trajectories and their associations with …

目的分析中小学生基线体质量指数(BMI) 水平及BMI 变化与随访8 年后(又称“终期”)
血压水平及血压偏高发生风险的关联, 为开展儿童青少年血压防控工作提供依据 …

Background The link between adiposity, metabolic abnormalities, and arterial disease
progression in children and adolescents remains poorly defined. We aimed to assess …

Background The dynamic monitoring of perioperative carcinoembryonic antigen (CEA) is
recommended by current colorectal cancer (CRC) guidelines, while the benefits of …

Background Individuals who are obese in childhood have an elevated risk of disease in
adulthood. However, whether childhood adiposity directly impacts intermediate markers of …