Cellular and molecular mechanisms of curcumin in prevention and treatment of disease
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …
Ion channels and channelopathies in glomeruli
A Staruschenko, R Ma, O Palygin… - Physiological …, 2023 - journals.physiology.org
An essential step in renal function entails the formation of an ultrafiltrate that is delivered to
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …
Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities
Y Cai, C Huang, M Zhou, S Xu, Y Xie, S Gao, Y Yang… - Phytomedicine, 2022 - Elsevier
Background Acute kidney injury (AKI) is a common complication in clinical inpatients, and it
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …
Health perspectives of a bioactive compound curcumin: A review
Abstract Curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) is a is
an important consituitents present in Curcuma longa L.(turmeric) rhizome. It is also a …
an important consituitents present in Curcuma longa L.(turmeric) rhizome. It is also a …
Renoprotective potentials of small molecule natural products targeting mitochondrial dysfunction
Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD),
have become critical clinical, socioeconomic, and public health concerns worldwide. The …
have become critical clinical, socioeconomic, and public health concerns worldwide. The …
Application of herbal traditional Chinese medicine in the treatment of acute kidney injury
HD Li, XM Meng, C Huang, L Zhang, XW Lv… - Frontiers in …, 2019 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid loss of renal
function, which may further develop into chronic kidney damage (CKD) or even end-stage …
function, which may further develop into chronic kidney damage (CKD) or even end-stage …
Dual-responsive curcumin-loaded nanoparticles for the treatment of cisplatin-induced acute kidney injury
T Lan, H Guo, X Lu, K Geng, L Wu, Y Luo… - …, 2022 - ACS Publications
Acute kidney injury (AKI) has been a global public health concern leading to high patient
morbidity and mortality in the world. Nanotechnology-mediated antioxidative therapy has …
morbidity and mortality in the world. Nanotechnology-mediated antioxidative therapy has …
CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage
JB Hu, SJ Li, XQ Kang, J Qi, JH Wu, XJ Wang… - Carbohydrate …, 2018 - Elsevier
Based on the abnormally increased expression of CD44 receptors on renal tubule epithelial
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …
Curcumin reduces LPS-induced septic acute kidney injury through suppression of lncRNA PVT1 in mice
W Huang, X Li, D Wang, Y Sun, Q Wang, Y Bu, F Niu - Life sciences, 2020 - Elsevier
Objective To investigate the protective effects of curcumin on LPS-induced septic acute
kidney injury and to explore its underlying molecular mechanisms. Methods A mouse model …
kidney injury and to explore its underlying molecular mechanisms. Methods A mouse model …
Curcumin protects against renal ischemia/reperfusion injury by regulating oxidative stress and inflammatory response
X Cui, L Lin, X Sun, L Wang… - … and Alternative Medicine, 2021 - Wiley Online Library
Objective. The aim of this study was to explore the pharmacological effects of curcumin on
oxidative stress and inflammatory response of renal dysfunction induced by renal …
oxidative stress and inflammatory response of renal dysfunction induced by renal …