Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Ion channels and channelopathies in glomeruli

A Staruschenko, R Ma, O Palygin… - Physiological …, 2023 - journals.physiology.org
An essential step in renal function entails the formation of an ultrafiltrate that is delivered to
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …

Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities

Y Cai, C Huang, M Zhou, S Xu, Y Xie, S Gao, Y Yang… - Phytomedicine, 2022 - Elsevier
Background Acute kidney injury (AKI) is a common complication in clinical inpatients, and it
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …

Health perspectives of a bioactive compound curcumin: A review

A Rauf, M Imran, IE Orhan, S Bawazeer - Trends in food science & …, 2018 - Elsevier
Abstract Curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) is a is
an important consituitents present in Curcuma longa L.(turmeric) rhizome. It is also a …

Renoprotective potentials of small molecule natural products targeting mitochondrial dysfunction

MA Rahman, S Akter, D Dorotea… - Frontiers in …, 2022 - frontiersin.org
Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD),
have become critical clinical, socioeconomic, and public health concerns worldwide. The …

Application of herbal traditional Chinese medicine in the treatment of acute kidney injury

HD Li, XM Meng, C Huang, L Zhang, XW Lv… - Frontiers in …, 2019 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid loss of renal
function, which may further develop into chronic kidney damage (CKD) or even end-stage …

Dual-responsive curcumin-loaded nanoparticles for the treatment of cisplatin-induced acute kidney injury

T Lan, H Guo, X Lu, K Geng, L Wu, Y Luo… - …, 2022 - ACS Publications
Acute kidney injury (AKI) has been a global public health concern leading to high patient
morbidity and mortality in the world. Nanotechnology-mediated antioxidative therapy has …

CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage

JB Hu, SJ Li, XQ Kang, J Qi, JH Wu, XJ Wang… - Carbohydrate …, 2018 - Elsevier
Based on the abnormally increased expression of CD44 receptors on renal tubule epithelial
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …

Curcumin reduces LPS-induced septic acute kidney injury through suppression of lncRNA PVT1 in mice

W Huang, X Li, D Wang, Y Sun, Q Wang, Y Bu, F Niu - Life sciences, 2020 - Elsevier
Objective To investigate the protective effects of curcumin on LPS-induced septic acute
kidney injury and to explore its underlying molecular mechanisms. Methods A mouse model …

Curcumin protects against renal ischemia/reperfusion injury by regulating oxidative stress and inflammatory response

X Cui, L Lin, X Sun, L Wang… - … and Alternative Medicine, 2021 - Wiley Online Library
Objective. The aim of this study was to explore the pharmacological effects of curcumin on
oxidative stress and inflammatory response of renal dysfunction induced by renal …