[HTML][HTML] Mutation rates, mutation frequencies, and proofreading-repair activities in RNA virus genetics

E Domingo, C García-Crespo, R Lobo-Vega, C Perales - Viruses, 2021 - mdpi.com
The error rate displayed during template copying to produce viral RNA progeny is a
biologically relevant parameter of the replication complexes of viruses. It has consequences …

[HTML][HTML] Peering into avian influenza a (H5N8) for a framework towards pandemic preparedness

JY Yeo, SKE Gan - Viruses, 2021 - mdpi.com
2014 marked the first emergence of avian influenza A (H5N8) in Jeonbuk Province, South
Korea, which then quickly spread worldwide. In the midst of the 2020–2021 H5N8 outbreak …

[HTML][HTML] Mechanistic interplay between HIV-1 reverse transcriptase enzyme kinetics and host SAMHD1 protein: Viral myeloid-cell tropism and genomic mutagenesis

NE Bowen, A Oo, B Kim - Viruses, 2022 - mdpi.com
Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) has been the
primary interest among studies on antiviral discovery, viral replication kinetics, drug …

Sagacious epitope selection for vaccines, and both antibody-based therapeutics and diagnostics: tips from virology and oncology

SKE Gan, SX Phua, JY Yeo - Antibody Therapeutics, 2022 - academic.oup.com
The target of an antibody plays a significant role in the success of antibody-based
therapeutics and diagnostics, and vaccine development. This importance is focused on the …

Effects of different delivery modes on teaching biomedical science practical skills in higher education during the 2021 pandemic measures

ZSL Heng, DWS Koh, JY Yeo, CP Ooi… - … and Molecular Biology …, 2022 - Wiley Online Library
The COVID‐19 pandemic related measures had augmented the rise of online education.
While online teaching had mitigated the negative impacts from educational institutional …

[HTML][HTML] APOBEC3 family proteins as drivers of virus evolution

M Jonathan, T Ikeda - Frontiers in Virology, 2023 - frontiersin.org
The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) family
consists of cytosine deaminases implicated in diverse and important biological functions …

[HTML][HTML] To plate or to simply unfreeze, that is the question for optimal plasmid extraction

RKR Thean, DXY Ong, ZSL Heng… - Journal of …, 2021 - ncbi.nlm.nih.gov
Many molecular biology applications require fast plasmid DNA extraction, spurring multiple
studies on how to speed up the process. It is regularly instructed in standard laboratory …

[HTML][HTML] Linear and non-linear analysis of heart rate variability in HIV-positive patients on two different antiretroviral therapy regimens

AJ Gonçalves, MVA Braga, PH Santana… - BMC Infectious …, 2021 - Springer
Background Cardiac autonomic dysfunction in HIV+ patients on different antiretroviral
therapy (ART) regimens has been described. We aimed to characterize parameters of heart …

[HTML][HTML] Yet Another Quick Assembly, Analysis and Trimming Tool (YAQAAT): A server for the automated assembly and analysis of Sanger sequencing data

DWS Koh, KF Chan, W Wu, SKE Gan - Journal of biomolecular …, 2021 - ncbi.nlm.nih.gov
Even with the ubiquity of Sanger sequencing, automated assembly software are
predominantly stand-alone software packages for desktop/laptop use with very few online …

Methods in bioinformatic and predictive virology

SKE Gan, EG Kostaki - Frontiers in Virology, 2023 - frontiersin.org
Viruses were cast under the international spotlight due to the global COVID-19 pandemic in
the early 2020s, renewing interests and applications in the field. With the pandemic still …