Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

The 5th edition of this indispensable resource captures the latest insights in neonatal
neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has …

Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …

Background Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-
ischaemia. We did a multicentre randomised controlled trial to find out if delayed head …

Abstract This Point of View article addresses neonatal encephalopathy (NE) presumably
caused by hypoxia–ischemia and the terminology currently in wide use for this disorder. The …

This is a clinical text about the commonest physical disability-the cerebral palsies. It follows
up on the authors' earlier work The Epidemiology of the Cerebral Palsies, and its focus is still …

Hypothermia has been proposed as a neuroprotective strategy. However, short-term cooling
after hypoxia-ischemia is effective only if started immediately during resuscitation. The aim of …

Phosphorus (31 P) spectra from the brains of severely birth-asphyxiated human infants are
commonly normal on the first day of life. Later, cerebral energy failure develops, which …

Acute post-asphyxial encephalopathy occurring around the time of birth remains a major
cause of death and disability. The recent seminal insight that allows active neuroprotective …

Severely birth-asphyxiated human infants develop delayed (“secondary”) cerebral energy
failure, which carries a poor prognosis, during the first few days of life. This study tested the …