[HTML][HTML] Improving study conduct and data quality in clinical trials of chronic pain treatments: IMMPACT recommendations

JS Gewandter, RH Dworkin, DC Turk, EG Devine… - The Journal of …, 2020 - Elsevier
The estimated probability of progressing from phase 3 analgesic clinical trials to regulatory
approval is approximately 57%, suggesting that a considerable number of treatments with …

[HTML][HTML] Design and conduct of confirmatory chronic pain clinical trials

N Katz - Pain reports, 2021 - journals.lww.com
The purpose of this article is to provide readers with a basis for understanding the emerging
science of clinical trials and to provide a set of practical, evidence-based suggestions for …

[HTML][HTML] Research design considerations for randomized controlled trials of spinal cord stimulation for pain: Initiative on Methods, Measurement, and Pain Assessment …

N Katz, RH Dworkin, R North, S Thomson, S Eldabe… - Pain, 2021 - journals.lww.com
Spinal cord stimulation (SCS) is an interventional nonpharmacologic treatment used for
chronic pain and other indications. Methods for evaluating the safety and efficacy of SCS …

John D. Loeser Award Lecture: Size does matter, but it isn't everything: the challenge of modest treatment effects in chronic pain clinical trials

SM Smith, M Fava, MP Jensen, OB Mbowe… - Pain, 2020 - journals.lww.com
Randomized clinical trials (RCTs) of treatments for pain have a long and distinguished
history. The earliest clinical trials not only identified analgesic medications and their …

[HTML][HTML] The Concerns About Pain (CAP) Scale: a patient-reported outcome measure of pain catastrophizing

D Amtmann, AM Bamer, KS Liljenquist, P Cowan… - The Journal of …, 2020 - Elsevier
Pain catastrophizing has been recognized as an important and consistent psychosocial
predictor of nearly every key pain-related outcome. The purpose of this study was to develop …

Understanding fraudulence in online qualitative studies: From the researcher's perspective

A Panicker, N Nurain, Z Ibrahim, CH Wang… - Proceedings of the CHI …, 2024 - dl.acm.org
Researchers are increasingly facilitating qualitative research studies online. While this has
made research more accessible for participation, there have been notable encounters with …

Detecting deception in our research participants: are your participants who you think they are?

ME McCaul, GS Wand - Alcoholism: Clinical and Experimental …, 2018 - Wiley Online Library
There is increasing awareness of the potential negative impacts of participant deception on
research, including possibly undermining reliability and reproducibility of study findings …

A crowdsourced intervention to promote hepatitis B and C testing among men who have sex with men in China: a nationwide online randomized controlled trial

T Fitzpatrick, W Tang, K Mollan, X Pan, PL Chan… - …, 2019 - thelancet.com
Background Crowdsourcing may be an effective strategy to develop test promotion
materials. We conducted an online randomized controlled trial (RCT) to evaluate a …

[HTML][HTML] Frequency of concealment, fabrication and falsification of study data by deceptive subjects

EG Devine, AM Pingitore, KN Margiotta… - Contemporary Clinical …, 2021 - Elsevier
Purpose Many studies have found evidence that research subjects engage in deceptive
practices while participating in health-related studies. Little is known, however, about how …

The Importance of Participant Tracking When Conducting Clinical Pharmacology Drug Trials.

KT Moore, MJ Fossler, I Younis - Journal of Clinical …, 2022 - search.ebscohost.com
The article reports that the American College of Clinical Pharmacology (ACCP) strongly
recommends the use of research participant databases, registries, or independent …