Osteoarthritis (OA) is an aging-related joint disease, pathologically featured with
degenerated articular cartilage and deformation of subchondral bone. OA has become the …

Large segmental bone regeneration remains a great challenge due to the lack of
vascularization in newly formed bone. Conventional strategies primarily combine bone …

With the global escalation of the aging process, the number of patients with bone diseases is
increasing year by year. Currently, there are limited effective treatments for bone diseases …

Several types of pediatric cancers reportedly contain high-frequency missense mutations in
histone H3, yet the underlying oncogenic mechanism remains poorly characterized. Here …

The skeleton is a dynamic tissue continuously adapting to mechanical stimuli. Although
matrix‐embedded osteocytes are considered as the key mechanoresponsive bone cells, all …

Hydrogels are particularly attractive as scaffolding materials for cartilage tissue engineering
because their high water content closely mimics the native extracellular matrix (ECM) …

A series of polymers capable of self-assembling into infinite networks via supramolecular
interactions have been designed, synthesized, and characterized for use in 3D printing …

The forkhead box O (FOXO) proteins are transcription factors involved in the differentiation of
many cell types. Type II collagen (Col2) Cre-Foxo1-knockout and Col2-Cre-Foxo1, 3, 4 triple …

A hyaluronic acid (HA) based injectable hydrogel with gradually increasing mechanical
properties was synthesized via photo-crosslinking reaction and thermal-induced Diels-Alder …

Recently alginate-based tissue repair scaffolds fabricated using 3D printing techniques have
been extensively examined for use in tissue engineering applications. However, their …