Emerging role of the spleen in the pharmacokinetics of monoclonal antibodies, nanoparticles and exosomes
M Cataldi, C Vigliotti, T Mosca, MR Cammarota… - International journal of …, 2017 - mdpi.com
After being absorbed, drugs distribute in the body in part to reach target tissues, in part to be
disposed in tissues where they do not exert clinically-relevant effects. Therapeutically …
disposed in tissues where they do not exert clinically-relevant effects. Therapeutically …
Chemotherapy of leishmaniasis: present challenges
Cutaneous and visceral leishmaniasis are amongst the most devastating infectious diseases
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
Leishmania–macrophage interactions: Insights into the redox biology
Leishmaniasis is a neglected tropical disease that affects about 350 million individuals
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …
Drug resistance in visceral leishmaniasis
HC Maltezou - BioMed Research International, 2010 - Wiley Online Library
Visceral leishmaniasis remains a public health problem worldwide. This illness was
included by the World Health Organization in the list of neglected tropical diseases targeted …
included by the World Health Organization in the list of neglected tropical diseases targeted …
Recent developments and future prospects in the treatment of visceral leishmaniasis
Limited therapeutic options in visceral leishmaniasis (VL) make the treatment of this
neglected disease very challenging. In addition to this, long treatment duration and toxic …
neglected disease very challenging. In addition to this, long treatment duration and toxic …
Molecular and immunological toxic effects of nanoparticles
RK Pandey, VK Prajapati - International journal of biological …, 2018 - Elsevier
Nanoparticles have emerged as a boon for the public health applications such as drug
delivery, diagnostic, and imaging. Biodegradable and non-bio degradable nanoparticles …
delivery, diagnostic, and imaging. Biodegradable and non-bio degradable nanoparticles …
Nanotechnology and human health: risks and benefits
AG Cattaneo, R Gornati, E Sabbioni… - Journal of applied …, 2010 - Wiley Online Library
Nanotechnology is expected to be promising in many fields of medical applications, mainly
in cancer treatment. While a large number of very attractive exploitations open up for the …
in cancer treatment. While a large number of very attractive exploitations open up for the …
Targeted killing of Leishmania donovani in vivo and in vitro with amphotericin B attached to functionalized carbon nanotubes
VK Prajapati, K Awasthi, S Gautam… - Journal of …, 2011 - academic.oup.com
Objectives This study describes the antileishmanial efficacy of the novel drug formulation of
amphotericin B (AmB) attached to functionalized carbon nanotubes (f-CNTs) and compares …
amphotericin B (AmB) attached to functionalized carbon nanotubes (f-CNTs) and compares …
Cell delivery of therapeutic nanoparticles
Nanomedicine seeks to manufacture drugs and other biologically relevant molecules that
are packaged into nanoscale systems for improved delivery. This includes known drugs …
are packaged into nanoscale systems for improved delivery. This includes known drugs …
Oral particle uptake and organ targeting drives the activity of amphotericin B nanoparticles
DR Serrano, A Lalatsa, MA Dea-Ayuela… - Molecular …, 2015 - ACS Publications
There are very few drug delivery systems that target key organs via the oral route, as oral
delivery advances normally address gastrointestinal drug dissolution, permeation, and …
delivery advances normally address gastrointestinal drug dissolution, permeation, and …