[HTML][HTML] Counterdiffusion methods applied to protein crystallization

F Otálora, JA Gavira, JD Ng, JM García-Ruiz - Progress in biophysics and …, 2009 - Elsevier
Accumulated experience during the last years on counterdiffusion crystallization methods
shows that they are a convenient and generally applicable way of optimizing solution crystal …

Mycobacterial shikimate pathway enzymes as targets for drug design

RG Ducati, LA Basso, DS Santos - Current drug targets, 2007 - ingentaconnect.com
The aetiological agent of tuberculosis (TB), Mycobacterium tuberculosis, is responsible for
millions of deaths annually. The increasing prevalence of the disease, the emergence of …

[HTML][HTML] Crystal growth of proteins, nucleic acids, and viruses in gels

B Lorber, C Sauter, A Théobald-Dietrich… - Progress in biophysics …, 2009 - Elsevier
Medium-sized single crystals with perfect habits and no defect producing intense and well-
resolved diffraction patterns are the dream of every protein crystallographer. Crystals of …

Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)‐2‐Benzyl‐3‐dehydroquinic Acids

A Peón, JM Otero, L Tizón, VFV Prazeres… - …, 2010 - Wiley Online Library
The binding mode of several substrate analogues,(2R)‐2‐benzyl‐3‐dehydroquinic acids 4,
which are potent reversible competitive inhibitors of type II dehydroquinase (DHQ2), the third …

Crystallization in gels

A Moreno, ME Mendoza - Handbook of Crystal Growth, 2015 - Elsevier
The aim of this chapter is to briefly review the recent applications of the gel method using
basic crystallization strategies to optimize the quality of small molecules (organic and …

Amino acid synthesis in plastids

M Lancien, PJ Lea, RA Azevedo - The structure and function of plastids, 2007 - Springer
Plants have the capacity to assimilate inorganic nitrogen and synthesize the twenty amino
acids required for normal protein synthesis, unlike animals that need at least nine essential …

Structure and function of enzymes of shikimate pathway

A Dev, S Tapas, S Pratap, P Kumar - Current Bioinformatics, 2012 - ingentaconnect.com
The shikimate pathway is found in microorganisms, fungi, plants and also in several
apicomplexan parasites. This metabolic pathway consists of seven enzymes and converts …

Granada crystallization facility-2: a versatile platform for crystallization in space

LA Gonzalez-Ramirez, J Carrera… - Crystal Growth and …, 2008 - ACS Publications
A facility for crystallization experiments in space named Granada Crystallization Facility-2
(GCF-2) is presented. GCF-2 is an inexpensive and compact modular platform featuring a …

Counterdiffusion protein crystallisation in microgravity and its observation with PromISS (Protein Microscope for the International Space Station)

I Zegers, L Carotenuto, C Evrard… - … Science and Technology, 2006 - Springer
The crystallisation by counterdiffusion is a very efficient technique for obtaining high-quality
protein crystals. A prerequisite for the use of counterdiffusion techniques is that mass …

Protein crystallization in hydrogel beads

R Willaert, I Zegers, L Wyns… - … Section D: Biological …, 2005 - journals.iucr.org
The use of hydrogel beads for the crystallization of proteins is explored in this contribution.
The dynamic behaviour of the internal precipitant, protein concentration and relative …