A guide to plasma membrane solute carrier proteins
MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …
of transporter proteins and their roles in human cells. The SLC superfamily currently …
The concept of folic acid in health and disease
Y Shulpekova, V Nechaev, S Kardasheva, A Sedova… - Molecules, 2021 - mdpi.com
Folates have a pterine core structure and high metabolic activity due to their ability to accept
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …
[HTML][HTML] An overview of nanoparticles in drug delivery: properties and applications
Today, in diverse medical and clinical fields, including cancer treatment, nanoscience has
evolved and evolved. Cancer and its forms, on the other hand, have been rumored and …
evolved and evolved. Cancer and its forms, on the other hand, have been rumored and …
[HTML][HTML] The ABCs of membrane transporters in health and disease (SLC series): introduction
MA Hediger, B Clémençon, RE Burrier… - Molecular aspects of …, 2013 - Elsevier
The field of transport biology has steadily grown over the past decade and is now
recognized as playing an important role in manifestation and treatment of disease. The SLC …
recognized as playing an important role in manifestation and treatment of disease. The SLC …
Folate production by probiotic bacteria
M Rossi, A Amaretti, S Raimondi - Nutrients, 2011 - mdpi.com
Probiotic bacteria, mostly belonging to the genera Lactobacillus and Bifidobacterium, confer
a number of health benefits to the host, including vitamin production. With the aim to produce …
a number of health benefits to the host, including vitamin production. With the aim to produce …
Folate-targeted therapies for cancer
W Xia, PS Low - Journal of medicinal chemistry, 2010 - ACS Publications
1.1. General Strategies in the Design of Tumor Targeted Therapeutics. Today's quest for
developing tumor-targeted therapies has naturally followed two nonoverlapping strategies …
developing tumor-targeted therapies has naturally followed two nonoverlapping strategies …
Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code
CM Porter, AW Truman, MC Truttmann - Journal of Biological Chemistry, 2020 - ASBMB
Cells must be able to cope with the challenge of folding newly synthesized proteins and
refolding those that have become misfolded in the context of a crowded cytosol. One such …
refolding those that have become misfolded in the context of a crowded cytosol. One such …
Folate-targeted therapeutic and imaging agents for cancer
PS Low, SA Kularatne - Current opinion in chemical biology, 2009 - Elsevier
Cancer therapies that exploit targeting ligands to deliver attached cytotoxic drugs selectively
to malignant cells are currently receiving significant attention. While antibody-targeted drugs …
to malignant cells are currently receiving significant attention. While antibody-targeted drugs …
Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues
R Zhao, LH Matherly, ID Goldman - Expert reviews in molecular …, 2009 - cambridge.org
Members of the family of B9 vitamins are commonly known as folates. They are derived
entirely from dietary sources and are key one-carbon donors required for de novo nucleotide …
entirely from dietary sources and are key one-carbon donors required for de novo nucleotide …
The antifolates
M Visentin, R Zhao, ID Goldman - Hematology/Oncology …, 2012 - hemonc.theclinics.com
The antifolates were the first class of antimetabolites to enter the clinics 65 years ago. These
agents disrupt the metabolic pathways that require one-carbon moieties supplied by the B9 …
agents disrupt the metabolic pathways that require one-carbon moieties supplied by the B9 …