Subarachnoid haemorrhage (SAH) causes early brain injury (EBI) that is mediated by effects
of transient cerebral ischaemia during bleeding plus effects of the subarachnoid blood …

The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …

Stroke is the primary cause of disability due to the brain's limited ability to regenerate
damaged tissue. After stroke, an increased inflammatory and immune response coupled …

Human erythropoietin (EPO) is an N-linked glycoprotein consisting of 166 aa that is
produced in the kidney during the adult life and acts both as a peptide hormone and …

In mammals, erythropoietin (EPO), produced in the kidney, is essential for bone marrow
erythropoiesis, and hypoxia induction of EPO production provides for the important …

The majority of research on reactive oxygen species (ROS) has focused on their cellular
toxicities. Stem cells generally have been thought to maintain low levels of ROS as a …

A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

Angiogenesis, the growth of new blood vessels, is a natural defense mechanism helping to
restore oxygen and nutrient supply to the affected brain tissue following an ischemic stroke …

Stroke causes cell death but also birth and migration of new neurons within sites of ischemic
damage. The cellular environment that induces neuronal regeneration and migration after …