Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

The lipid bilayer component of biological membranes is important for the distribution,
organization, and function of bilayer-spanning proteins. This regulation is due to both …

This review article is divided into three sections. In Section 1, a short biographical note on
Freiherr von Grotthuss is followed by a detailed summary of the main findings and ideas …

The measurement of anisotropic spin interactions, such as residual dipolar couplings, in
partially ordered solutions can provide valuable information on biomolecular structure. While …

Membrane protein function is regulated by the host lipid bilayer composition. This regulation
may depend on specific chemical interactions between proteins and individual molecules in …

The linear peptide gramicidin forms prototypical ion channels specific for monovalent
cations and has been extensively used to study the organization, dynamics and function of …

Bicelles are a versatile class of model membranes known to align in magnetic fields.
Bicelles were originally developed for use in solid-state NMR studies of …

The free energy governing K+ conduction through gramicidin A channels is characterized by
using over 0.1 μs of all-atom molecular dynamics simulations with explicit solvent and …

Much of postgenomic biochemistry and all of structural biology are based on the premise
that the starting point for both understanding specific biochemical processes, such as affinity …

Macromolecular structure determination by NMR spectroscopy has been absolutely
dependent on resonance assignments. Indeed, inaccurate assignments have frequently led …