This review of the familial tumor syndromes involving the endocrine organs is focused on
discussing the main updates on the upcoming fifth edition of the WHO Classification of …

Familial non-medullary thyroid cancer (FNMTC) constitutes 3–9% of all thyroid cancers. Out
of all FNMTC cases, only 5% in the syndromic form has well-studied driver germline …

Background: Papillary thyroid carcinoma (PTC) shows high heritability, yet efforts to find
predisposing genes have been largely negative. Objectives: The objective of this study was …

Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the
increasing incidence of NMTC in recent years, the familial form of the disease has also …

It is widely accepted that thyroid cancer is strongly determined by the individual genetic
background. In this regard, it is expected that sporadic thyroid cancer is the result of multiple …

The biology and the genetics of Hürthle cell tumors are reviewed starting from the
characterization and differential diagnosis of the numerous benign and malignant …

Cancer derived from thyroid follicular epithelial cells is common; it represents the most
common endocrine malignancy. The molecular features of sporadic tumors have been …

Pituitary adenomas are common tumors of the adenohypophysis which can cause
considerable morbidity, due to excessive hormonal secretion or compression and local …

Background: Nonmedullary thyroid cancers (NMTC) originate from the follicular cells of the
thyroid gland and account for over 90% of all thyroid cancers. About 3–10% of the NMTCs …

Background: Our genome sequencing analysis revealed a frameshift mutation in the
shelterin gene TINF2 in a large family with individuals affected with papillary thyroid …