Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …
sources is currently an advancing area in industrial research. The model yeast …
Yarrowia lipolytica Strains and Their Biotechnological Applications: How Natural Biodiversity and Metabolic Engineering Could Contribute to Cell Factories …
C Madzak - Journal of Fungi, 2021 - mdpi.com
Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …
Yarrowia lipolytica appears as one of the most attractive for a large range of white …
Comparison of yeasts as hosts for recombinant protein production
AM Vieira Gomes, T Souza Carmo, L Silva Carvalho… - Microorganisms, 2018 - mdpi.com
Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …
genetic engineering tools, which represented a compelling alternative to protein extraction …
Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production
Economic feasibility of biosynthetic fuel and chemical production hinges upon harnessing
metabolism to achieve high titre and yield. Here we report a thorough genotypic and …
metabolism to achieve high titre and yield. Here we report a thorough genotypic and …
Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR–Cas9-Mediated Genome Editing in Yarrowia lipolytica
CM Schwartz, MS Hussain, M Blenner… - ACS synthetic …, 2016 - ACS Publications
The oleaginous yeast Yarrowia lipolytica is a valuable microbial host for chemical
production because it has a high capacity to synthesize, modify, and store intracellular lipids; …
production because it has a high capacity to synthesize, modify, and store intracellular lipids; …
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
Z Xue, PL Sharpe, SP Hong, NS Yadav, D Xie… - Nature …, 2013 - nature.com
The availability of the omega-3 fatty acids eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) is currently limited because they are produced mainly by …
docosahexaenoic acid (DHA) is currently limited because they are produced mainly by …
Metabolic engineering in the host Yarrowia lipolytica
The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …
valuable host for the production of a variety of both lipid and nonlipid chemical products …
Production of recombinant proteins by yeast cells
Yeasts are widely used in production of recombinant proteins of medical or industrial
interest. For each individual product, the most suitable expression system has to be …
interest. For each individual product, the most suitable expression system has to be …
Hydrophobic substrate utilisation by the yeast Yarrowia lipolytica, and its potential applications
The alkane-assimilating yeast Yarrowia lipolytica degrades very efficiently hydrophobic
substrates such as n-alkanes, fatty acids, fats and oils for which it has specific metabolic …
substrates such as n-alkanes, fatty acids, fats and oils for which it has specific metabolic …
EasyCloneYALI: CRISPR/Cas9‐Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
C Holkenbrink, MI Dam, KR Kildegaard… - Biotechnology …, 2018 - Wiley Online Library
The oleaginous yeast Yarrowia lipolytica is an emerging host for production of fatty acid‐
derived chemicals. To enable rapid iterative metabolic engineering of this yeast, there is a …
derived chemicals. To enable rapid iterative metabolic engineering of this yeast, there is a …