Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and
perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic …

Based on global estimates, almost 10% of adults have diabetes, of whom 40% are estimated
to also have chronic kidney disease (CKD). Almost 2 decades ago, treatments targeting the …

Arterial hypertension is a common condition worldwide and an important predictor of several
complicated diseases. Arterial hypertension can be triggered by many factors, including …

Abstract Purpose of Review Several interrelated mechanisms promote the development of
hypertension in obesity, often contributing to end organ damage including cardiovascular …

Pathophysiologically lower BPs results in less strain on the LV, and, thus, more aggressive
BP control may have benefits in terms of LV hypertrophy, myocardial fibrosis, diastolic …

The evolution of metabolic and cardiovascular disease (CVD) complications after liver
transplantation (LT) is poorly characterized. We aim to illustrate the prevalence of obesity …

Abstract Characterization of mice with cell-specific deletion or overexpression of the
mineralocorticoid receptor (MR) shed a new light on its role in health and disease …

The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors including insulin
resistance (IR), dyslipidemia, and hypertension, which may also foster development of …

Obese subjects often have hypertension and related cardiovascular and renal diseases, and
this has become a serious worldwide health problem. In obese subjects, impaired renal …

Atrial natriuretic peptide (ANP) is a cardiac hormone with pleiotropic cardiovascular and
metabolic properties including vasodilation, natriuresis and suppression of the renin …