The Clostridium genus is a large, diverse group consisting of Gram-positive, spore-forming,
obligate anaerobic firmicutes. Among this group are historically notorious pathogens as well …

Accumulation of phosphorylated intermediates during cellular metabolism can have wide-
ranging toxic effects on many organisms, including humans and the pathogens that infect …

Glucose homeostasis is strictly controlled in all domains of life. Bacteria that are unable to
balance intracellular sugar levels and deal with potentially toxic phosphosugars cease …

Marine benthic invertebrates are frequently exposed to fluctuating oxygen levels resulting in
hypoxia-reoxygenation (H/R) stress in the intertidal, estuarine and shallow coastal habitats …

Central metabolism is a topic that has been studied for decades, and yet, this process is still
not fully understood in Escherichia coli, perhaps the most amenable and well-studied model …

BACKGROUND: Metabolomics has been proposed to be a hallmark of cancer, yet a
systematic characterization of a metabolite and metabolic pathways in human …

In bacteria, the canonical mechanism of translational repression by small RNAs (sRNAs)
involves sRNA-mRNA base pairing that occludes the ribosome binding site (RBS), directly …

The vital role of bacterial small RNAs (sRNAs) in cellular regulation is now well-established.
Although many diverse mechanisms by which sRNAs bring about changes in gene …

Bacteria adapt to ever-changing habitats through specific responses to internal and external
stimuli that result in changes in gene regulation and metabolism. One internal metabolic cue …

In bacteria like Escherichia coli, the accumulation of glucose-6-phosphate (G6P) or its
analogs such as α-methyl glucoside-6-phosphate (αMG6P) results in stress that appears in …