Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

African horse sickness is a devastating disease that causes great suffering and many
fatalities amongst horses in sub-Saharan Africa. It is caused by nine different serotypes of …

Baculovirus and insect cell culture technologies have mostly been limited to research
laboratories for the transient expression of target proteins for drug development purposes …

Virus-like particles (VLPs) have been produced as candidate vaccines in plants virtually
since the introduction of biofarming. Even today, VLPs remain the best candidates for safe …

Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …

The reverse genetics technology for bluetongue virus (BTV) has been used in combination
with complementing cell lines to recover defective BTV-1 mutants. To generate a potential …

Bluetongue (BT) is a haemorrhagic disease of wild and domestic ruminants with a huge
economic worldwide impact on livestock. The disease is caused by BT-virus transmitted by …

Developing vaccines for livestock provides researchers with the opportunity to perform
efficacy testing in the natural hosts. This enables the evaluation of different strategies …

Bluetongue virus (BTV) causes the hemorrhagic disease bluetongue (BT) in ruminants. The
best way to control outbreaks is vaccination. Currently, conventionally modified-live and …

The baculovirus-insect cell expression system is a well-established technology for the
production of heterologous viral (glyco) proteins in cultured cells, applicable for basic …