Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

SM Gomha, TA Salah, AO Abdelhamid - Monatshefte für Chemie …, 2015 - Springer
Abstract Two series of novel 2-[[1-(5-methyl-1-phenyl-5-substituted-1 H-pyrazol-4-yl)
ethylidene] hydrazono]-3-phenyl-2, 3-dihydro-1, 3, 4-thiadiazole derivatives and 2-[5-(4 …

Synthesis and cytotoxic activity of some novel benzocoumarin derivatives under solvent free conditions

A Abdel-Aziem, HRM Rashdan… - … Chemistry Letters and …, 2019 - Taylor & Francis
In the present study, a rapid, less expensive, clean and environmental friendly route to
synthesis new pyrazoles, pyrazolopyridazines and condensed pyrimidines was developed …

Reactions of heterocyclic compounds with nitrilimines and their precursors

AS Shawali - Chemical reviews, 1993 - ACS Publications
A large and valuable store of review literature on many aspects of the chemistry of
heterocyclic com-pounds has grown up over the last few decades. 1 However, the …

[HTML][HTML] A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity

SM Gomha, KD Khalil - Molecules, 2012 - mdpi.com
Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series
of 3-[1-(4-substituted-5-(aryldiazenyl) thiazol-2-yl) hydrazono) ethyl]-2 H-chromen-2-ones 5a …

Synthesis and anticancer activity of arylazothiazoles and 1, 3, 4-thiadiazoles using chitosan-grafted-poly (4-vinylpyridine) as a novel copolymer basic catalyst

SM Gomha, SM Riyadh, EA Mahmmoud… - Chemistry of …, 2015 - Springer
A novel series of 4-substituted 5-arylazo-2-[1-(pyrrol-3-yl) ethylidenehydrazinyl] thiazoles
and 5-arylazo-2-[1-(pyrrol-3-yl) ethylidenehydrazinyl]-2, 3-dihydrothiazol-3-amines was …

[HTML][HTML] Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating …

SM Gomha, SA Ahmed, AO Abdelhamid - Molecules, 2015 - mdpi.com
Reactions of hydrazonoyl halides and each of methyl 2-(1-(5-methyl-1-phenyl-1 H-1, 2, 3-
triazol-4-yl) ethylidene) hydrazine-1-carbodithioate and 2-(1-(5-methyl-1-phenyl-1 H-1, 2, 3 …

Synthesis and Anticancer Activity of 1, 3, 4Thiadiazole and 1, 3Thiazole Derivatives Having 1, 3, 4Oxadiazole Moiety

KM Dawood, SM Gomha - Journal of Heterocyclic Chemistry, 2015 - Wiley Online Library
Reaction of 1, 3, 4oxadiazolylphenylthiourea 3 with hydrazonoyl halides gave the
corresponding 1, 3, 4oxadiazolylimino1, 3, 4thiadiazoles. Also, treatment of 3 with ethyl …

[HTML][HTML] Synthesis of new 3-heteroarylindoles as potential anticancer agents

AO Abdelhamid, SM Gomha, NA Abdelriheem… - Molecules, 2016 - mdpi.com
2-(3-(1 H-Indol-3-yl)-5-(p-tolyl)-4, 5-dihydro-1 H-pyrazol-1-yl)-4-substituted-5-(substituted
diazenyl) thiazoles and 2-(1 H-indol-3-yl)-9-substituted-4, 7-disubstituted pyrido [3, 2-e][1, 2 …

[HTML][HTML] Utility of 3-Acetyl-6-bromo-2H-chromen-2-one for the Synthesis of New Heterocycles as Potential Antiproliferative Agents

SM Gomha, YH Zaki, AO Abdelhamid - Molecules, 2015 - mdpi.com
Coumarin derivatives containing pyrazolo [1, 5-a] pyrimidine, tetrazolo [1, 5-a] pyrimidine,
imidazo [1, 2-a] pyrimidine, pyrazolo [3, 4-d] pyrimidine, 1, 3, 4-thiadiazoles and thiazoles …

[PDF][PDF] Synthetic utility of ethylidenethiosemicarbazide: synthesis and anti-cancer activity of 1, 3-thiazines and thiazoles with imidazole moiety

SM Gomha, SM Riyadh, IM Abbas… - …, 2013 - triggered.stanford.clockss.org
Reactions of ethylidenethiosemicarbazide 3 with DMAD 4 or substituted
methylenemalononitriles 8 gave thiazolidin-4-one 6 or 1, 3-thiazine derivatives (10, 11) …