Recent progress in catalytic synthesis of 1, 2, 3-triazoles

A De Nino, L Maiuolo, P Costanzo, V Algieri, A Jiritano… - Catalysts, 2021 - mdpi.com
1, 2, 3-triazoles represent a functional heterocyclic core that has been at the center of
modern organic chemistry since the beginning of click chemistry. Being a versatile …

Metal-free syntheses of N-functionalized and NH-1, 2, 3-triazoles: an update on recent developments

T Opsomer, W Dehaen - Chemical Communications, 2021 - pubs.rsc.org
An overview of the latest developments in the metal-free synthesis of non-benzo-fused N-
functionalized and NH-1, 2, 3-triazoles is provided in this feature article. Synthetic studies …

Progress in synthetic trends followed for the development of 1, 2, 3-triazole derivatives: a review

MM Masood - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
Since the beginning of click chemistry, 1, 2, 3-triazoles has been at the center of modern
organic chemistry. This versatile framework has found broad applications in organic …

Synthesis and Characterization of Novel 2-(1,2,3-Triazol-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazoles and 2-(4,5-Dihydro-1H-pyrazol-1-yl)-4-(1H-1,2,3-triazol-4-yl) …

BM Kariuki, BF Abdel-Wahab, HA Mohamed… - Molecules, 2022 - mdpi.com
Reactions of 1-(5-methyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-ones and benzaldehydes in
ethanol under basic conditions gave the corresponding chalcones. Reactions of the …

Substituted 1, 2, 3-triazoles: a new class of nitrification inhibitors

BI Taggert, C Walker, D Chen, U Wille - Scientific Reports, 2021 - nature.com
Nitrogen (N) fertilisers amended with nitrification inhibitors can increase nitrogen use
efficiencies in agricultural systems but the effectiveness of existing commercial inhibitor …

Insights into the Efficacy and Binding Mode of 1, 4-Disubstituted 1, 2, 3-Triazoles─ A New Class of Agricultural Nitrification Inhibitors

SC Yildirim, BI Taggert, RM Walker… - … Agricultural Science & …, 2023 - ACS Publications
Recently, 1, 4-disubstituted 1, 2, 3-triazoles were reported by us as a new class of
nitrification inhibitors, which can outperform the commercial compound 3, 4 …

Design and characterization of a pyridone-containing EZH2 inhibitor phosphate prodrug

PP Kung, C Fan, HJ Gukasyan, B Huang… - Journal of Medicinal …, 2021 - ACS Publications
A pyridone-derived phosphate prodrug of an enhancer of zeste homolog 2 (EZH2) inhibitor
was designed and synthesized to improve the inhibitor's aqueous solubility. This prodrug …

Iodine‐Mediated Condensation–Cyclization of α‐Azido Ketones with p‐Toluenesulfonyl Hydrazide for Synthesis of 4‐Aryl‐NH‐1,2,3‐Triazoles

MT Ren, M Li, AJ Wang, J Gao… - European Journal of …, 2020 - Wiley Online Library
A molecular iodine mediated condensation–cyclization reaction for the synthesis of 4‐aryl‐
NH‐1, 2, 3‐triazoles has been developed from readily available α‐azido acetophenones …

Emerging aspects of triazole in organic synthesis: exploring its potential as a Gelator

RJ Vasanthan, S Pradhan… - Current Organic …, 2024 - ingentaconnect.com
Cu (I)-catalyzed azide− alkyne 1, 3-dipolar cycloaddition (CuAAC)-commonly known as the
“click reaction”-serves as the most effective and highly reliable tool for facile construction of …

Rapid, One-Step Synthesis of α-Ketoacetals via Electrophilic Etherification

TJ Paris, C Schwartz, E Sundall… - The Journal of …, 2021 - ACS Publications
Herein, we report a rapid, one-step synthesis of α-ketoacetals via electrophilic etherification
of α-alkoxy enolates and monoperoxyacetals. Methyl, primary, and secondary α-ketoacetals …