The last decade has seen a surge of evidence supporting the existence of the transition of
the multicellular tissue from a collective material phase that is regarded as being jammed to …

The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial
in the processes of cell differentiation and proliferation. However, it is unclear to what extent …

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

The airway epithelium serves as the interface between the host and external environment. In
many chronic lung diseases, the airway is the site of substantial remodeling after injury …

The process in which locally confined epithelial malignancies progressively evolve into
invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a …

The molecular mechanisms underlying the clinical manifestations of coronavirus disease
2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and …

Basic human functions such as breathing and digestion require mechanical stretching of
cells and tissues. However, when it comes to laboratory experiments, the mechanical …

Epithelial cell function is modulated by mechanical forces imparted by the extracellular
environment. The transmission of forces onto the cytoskeleton by modalities such as …

Involvement of small airways, those of< 2 mm in internal diameter, is present in all stages of
asthma and contributes substantially to its pathophysiologic expression. Therefore, small …

In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite
event is collective epithelial cellular migration. For example, cells at the advancing front of a …