Exosomes are cell-derived membranous structures primarily involved in the delivery of the
payload to the recipient cells, and they play central roles in carcinogenesis and metastasis …

Febuxostat (FBX), a xanthine oxidase inhibitor, is known to improve renal function and can
show promise as a therapeutic agent for preventing drug-induced nephrotoxicity. This study …

Nephrotoxicity is a serious complication that limits the clinical use of gentamicin (GEN).
Parthenolide (PTL) is a sesquiterpene lactone derived from feverfew with various …

Background: Nephrotoxicity refers to the toxigenic impact of compounds and medications on
kidney function. There are a variety of drug formulations, and some medicines that may …

Arsenic compounds, which are used in different industries like pesticide manufacturing,
cause severe toxic effects in almost all organs, including the kidneys. Since the primary …

The primary limitation of gentamicin (Gm) treatment is its potential to induce nephrotoxicity,
which can restrict both its duration and efficacy. This study aims to investigate the protective …

Abstract Ginger (Zingiber officinale Roscoe), a widely consumed medicinal plant, contains
various bioactive phenolic compounds, including gingerols, shogaols, paradol, and …

Background/aim Doxorubicin (DOX) is a highly effective chemotherapy medicine commonly
used to treat breast cancer; yet, despite its clinical efficacy, it usually causes chemobrain. As …

Ethnopharmacological relevance Manilkara zapota (L.) P. Royen, also termed sapodilla or
chikoo, is a significant plant in ethnomedicine because of its long history of traditional …

Gentamicin (Genta)-induced nephrotoxicity poses a significant clinical challenge due to its
detrimental effects on kidney function. Clopidogrel (Clop), an antiplatelet drug known for its …