Mechanism of deep brain stimulation: inhibition, excitation, or disruption?
S Chiken, A Nambu - The neuroscientist, 2016 - journals.sagepub.com
Deep brain stimulation (DBS), applying high-frequency electrical stimulation to deep brain
structures, has now provided an effective therapeutic option for treatment of various …
structures, has now provided an effective therapeutic option for treatment of various …
The mechanisms of action of deep brain stimulation and ideas for the future development
Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …
A large-scale model of the functioning brain
A central challenge for cognitive and systems neuroscience is to relate the incredibly
complex behavior of animals to the equally complex activity of their brains. Recently …
complex behavior of animals to the equally complex activity of their brains. Recently …
Subthalamic nucleus deep brain stimulation in primary cervical dystonia
JL Ostrem, CA Racine, GA Glass, JK Grace, MM Volz… - Neurology, 2011 - AAN Enterprises
Objectives: The globus pallidus internus (GPi) has been the primary target for deep brain
stimulation (DBS) to treat severe medication-refractory dystonia. Some patients with primary …
stimulation (DBS) to treat severe medication-refractory dystonia. Some patients with primary …
The external globus pallidus: progress and perspectives
DJ Hegeman, ES Hong… - European Journal of …, 2016 - Wiley Online Library
The external globus pallidus (GP e) of the basal ganglia is in a unique and powerful position
to influence processing of motor information by virtue of its widespread projections to all …
to influence processing of motor information by virtue of its widespread projections to all …
[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?
T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …
The Canadian multicentre study of deep brain stimulation for cervical dystonia
ZHT Kiss, K Doig-Beyaert, M Eliasziw, J Tsui… - Brain, 2007 - academic.oup.com
Deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) is an effective
treatment for generalized dystonia. Its role in the management of other types of dystonia is …
treatment for generalized dystonia. Its role in the management of other types of dystonia is …
Treatment of dystonia with deep brain stimulation
JL Ostrem, PA Starr - Neurotherapeutics, 2008 - Springer
Pallidal deep brain stimulation (DBS) is an established treatment option for medically
refractive dystonia. The mechanism by which globus pallidus pars interna (GPi) DBS …
refractive dystonia. The mechanism by which globus pallidus pars interna (GPi) DBS …
Latest view on the mechanism of action of deep brain stimulation
How does deep brain stimulation (DBS) applied at high frequency (100 Hz and above, HFS)
in diverse points of cortico‐basal ganglia thalamo‐cortical loops alleviate symptoms of …
in diverse points of cortico‐basal ganglia thalamo‐cortical loops alleviate symptoms of …
Pathological basal ganglia activity in movement disorders
T Wichmann, JO Dostrovsky - Neuroscience, 2011 - Elsevier
Our understanding of the pathophysiology of movement disorders and associated changes
in basal ganglia activities has significantly changed during the last few decades. This …
in basal ganglia activities has significantly changed during the last few decades. This …