Nanoparticles for radiooncology: Mission, vision, challenges

LA Kunz-Schughart, A Dubrovska, C Peitzsch, A Ewe… - Biomaterials, 2017 - Elsevier
Cancer is one of the leading non-communicable diseases with highest mortality rates
worldwide. About half of all cancer patients receive radiation treatment in the course of their …

Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing both Kinase-Dependent and Kinase-Independent Functions of the Receptor

Y Zhang - Pharmacological Reviews, 2023 - ASPET
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, is activated by ligand
binding, overexpression, or mutation. It is well known for its tyrosine kinase-dependent …

EGFR-directed monoclonal antibodies in combination with chemotherapy for treatment of non-small-cell lung cancer: an updated review of clinical trials and new …

F Agustoni, K Suda, H Yu, S Ren, CJ Rivard… - Cancer treatment …, 2019 - Elsevier
Lung cancer still represents one of the most common and fatal neoplasm, accounting for
nearly 30% of all cancer-related deaths. Targeted therapies based on molecular tumor …

Nimotuzumab plus paclitaxel and cisplatin as the first line treatment for advanced esophageal squamous cell cancer: A single centre prospective phase II trial

M Lu, X Wang, L Shen, J Jia, J Gong, J Li, J Li… - Cancer …, 2016 - Wiley Online Library
Nimotuzumab (N) is a humanized anti‐epidermal growth factor receptor monoclonal
antibody. This prospective, single‐armed, open label phase II study was conducted to …

Necitumumab for the treatment of advanced non-small-cell lung cancer

A Diaz-Serrano, A Sanchez-Torre, L Paz-Ares - Future Oncology, 2018 - Taylor & Francis
Personalized patient-precise medicine is being gradually incorporated into clinical practice
for the treatment of non-small-cell lung cancer (NSCLC). The EGFR pathway has been …

[HTML][HTML] Uniqueness of lung cancer in Southeast Asia

V Noronha, A Budukh, P Chaturvedi, S Anne… - The Lancet Regional …, 2024 - thelancet.com
Lung cancer varies between Caucasians and Asians. There have been differences recorded
in the epidemiology, genomics, standard therapies and outcomes, with variations according …

Critical roles of EGFR family members in breast cancer and breast cancer stem cells: targets for therapy

LS Steelman, T Fitzgerald… - Current …, 2016 - ingentaconnect.com
The roles of the epidermal growth factor receptor (EGFR) signaling pathway in various
cancers including breast, bladder, brain, colorectal, esophageal, gastric, head and neck …

Skin toxicity with anti-EGFR monoclonal antibody in cancer patients: a meta-analysis of 65 randomized controlled trials

J Li, H Yan - Cancer Chemotherapy and Pharmacology, 2018 - Springer
We performed a meta-analysis to fully investigate the skin toxicities of anti-EGFR
monoclonal antibody (EGFR-MoAbs) in cancer patients. The relevant studies of the …

[HTML][HTML] Racotumomab in non-small cell lung cancer as maintenance and second-line treatment

HH Cáceres-Lavernia, E Nenínger-Vinageras… - MEDICC …, 2022 - SciELO Public Health
INTRODUCTION Racotumomab is a therapeutic vaccine based on a monoclonal anti-
idiotypic antibody developed by the Molecular Immunology Center in Havana, Cuba, that is …

A study on the effect of IL-6 gene polymorphism on the prognosis of non-small-cell lung cancer

W Jia, GH Fei, JG Hu, XW Hu - OncoTargets and therapy, 2015 - Taylor & Francis
Background Lung cancer is one of the most commonly diagnosed clinical diseases. IL-6 is a
multifunctional cytokine that is related to chemotactic factors and tumor biological …