Pain-related cortico-limbic plasticity and opioid signaling

V Neugebauer, P Presto, V Yakhnitsa, N Antenucci… - …, 2023 - Elsevier
Neuroplasticity in cortico-limbic circuits has been implicated in pain persistence and pain
modulation in clinical and preclinical studies. The amygdala has emerged as a key player in …

Laterality and mental disorders in the postgenomic age–A closer look at schizophrenia and language lateralization

S Ocklenburg, O Güntürkün, K Hugdahl… - … & Biobehavioral Reviews, 2015 - Elsevier
Most people are right-handed and show left-hemispheric language lateralization, but a
minority exhibits left-handedness and right-hemispheric language lateralization. This …

[HTML][HTML] Interindividual variability and lateralization of μ-opioid receptors in the human brain

T Kantonen, T Karjalainen, J Isojärvi, P Nuutila… - NeuroImage, 2020 - Elsevier
Alterations in the brain's μ-opioid receptor (MOR) system have been associated with several
neuropsychiatric disorders. Central MOR availability also varies considerably in healthy …

Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

N Lukoyanov, H Watanabe, LS Carvalho… - Elife, 2021 - elifesciences.org
Brain injuries can interrupt descending neural pathways that convey motor commands from
the cortex to spinal motoneurons. Here, we demonstrate that a unilateral injury of the …

Opiate drugs with abuse liability hijack the endogenous opioid system to disrupt neuronal and glial maturation in the central nervous system

KF Hauser, PE Knapp - Frontiers in pediatrics, 2018 - frontiersin.org
The endogenous opioid system, comprised of multiple opioid neuropeptide and receptor
gene families, is highly expressed by developing neural cells and can significantly influence …

Endogenous opiates and behavior: 2015

RJ Bodnar - Peptides, 2017 - Elsevier
This paper is the thirty-eighth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2015 …

Systemic ghrelin treatment induces rapid, transient, and asymmetric changes in the metabolic activity of the mouse brain

PN De Francesco, G Fernandez, M Uriarte… - …, 2023 - karger.com
Introduction: Ghrelin regulates a variety of functions by acting in the brain. The targets of
ghrelin in the mouse brain have been mainly mapped using immunolabeling against c-Fos …

Intentionality in frontal asymmetry research

J Hewig - Psychophysiology, 2018 - Wiley Online Library
The present article provides a theoretical viewpoint on several aspects in frontal asymmetry
research. Based on a brief overview of evidence related to an approach‐avoidance …

Central neural substrates involved in temperature discrimination, thermal pain, thermal comfort, and thermoregulatory behavior

D Arthur - Handbook of clinical neurology, 2018 - Elsevier
A phylogenetically novel pathway that emerged with primate encephalization is described,
which conveys high-fidelity cutaneous thermosensory activity in" labeled lines" to a …

Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

H Watanabe, O Nosova, D Sarkisyan… - Brain …, 2020 - academic.oup.com
Unilateral traumatic brain injury and stroke result in asymmetric postural and motor deficits
including contralateral hemiplegia and hemiparesis. In animals, a localized unilateral brain …