Evidence for the involvement of matrix-degrading metalloproteinases (MMPs) in atherosclerosis

BA Brown, H Williams, SJ George - Progress in molecular biology and …, 2017 - Elsevier
Atherosclerosis leads to blockage of arteries, culminating in myocardial infarction, and
stroke. The involvement of matrix-degrading metalloproteinases (MMPs) in atherosclerosis …

Genetic polymorphism of MMP family and coronary disease susceptibility: a meta-analysis

M Li, J Shi, L Fu, H Wang, B Zhou, X Wu - Gene, 2012 - Elsevier
The issue that genetic polymorphism of matrix metalloproteinase (MMP) family is in
association with coronary disease is controversial. So we did a meta-analysis to clarify it …

Genetic polymorphism of interleukin-6 gene and susceptibility to acute myocardial infarction

H Vakili, SMH Ghaderian, RA Najar… - Coronary artery …, 2011 - journals.lww.com
Objectives Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis.
Genes coding for cytokines such as interleukin-6 (IL-6) are candidates for predisposing to …

Tumor necrosis factor-α: investigation of gene polymorphism and regulation of TACE–TNF-α system in patients with acute myocardial infarction

SMH Ghaderian, R Akbarzadeh Najar… - Molecular biology …, 2011 - Springer
A polymorphism within tumor necrosis factor-α (TNF-α) gene promoter and contribution of
TNF-α converting enzyme (TACE) have been reported to be associated with TNF-α …

C-reactive protein (CRP) gene polymorphisms: implication in CRP plasma levels and susceptibility to acute myocardial infarction

R Akbarzadeh Najar, SMH Ghaderian… - Molecular biology …, 2012 - Springer
C-reactive protein (CRP) is one of the many molecular factors involved in pathogenesis of
coronary artery disease which its plasma levels are associated with increased risk of …

Features of vulnerable plaques and clinical outcome of UA/NSTEMI: relationship with matrix metalloproteinase functional polymorphisms

N Fiotti, ME Moretti, R Bussani, N Altamura, F Zamolo… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: To assess the association of matrix metalloproteinases (MMP) genetic
polymorphism (PM) with plaques vulnerability and clinical outcome of acute vascular events …

Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease

I Jguirim-Souissi, A Jelassi, A Slimani… - Coronary artery …, 2011 - journals.lww.com
Objectives In this study, we investigated the association between matrix metalloproteinase-1
(MMP-1) G-1607GG, MMP-12 A-82G and MMP-12 A1082G genotypes and haplotypes and …

Tissue-specific relaxin-2 is differentially associated with the presence/size of an arterial aneurysm and the severity of atherosclerotic disease in humans

K Papoutsis, A Kapelouzou, G Georgiopoulos… - Acta Pharmacologica …, 2020 - nature.com
Circulating or tissue-related biomarkers are of clinical value for risk stratification in patients
with abdominal aortic aneurysms. Relaxin-2 (RL2) has been linked to the presence and size …

Early citalopram treatment increases mortality due to left ventricular rupture in mice after myocardial infarction

A Frey, VM Saxon, S Popp, M Lehmann… - Journal of molecular and …, 2016 - Elsevier
Aims Both anxiety and depression are common and independent outcome predictors in
patients after myocardial infarction (MI). However, it is unclear whether and how anti …

Associations among periostin gene polymorphisms, clinical parameters and heart failure: a case–control study in 1104 Chinese individuals

F Wang, Y Song, Y Jiang, C Yang… - Journal of Cardiovascular …, 2011 - journals.lww.com
Aims To determine the associations among periostin gene polymorphisms, clinical
parameters and heart failure in a Chinese population. Methods In total, 464 patients with …