Immunosenescence is defined as the progressive deterioration of the immune system with
aging. Immunosenescence stifles the generation of protective B and T cell-mediated …

ABSTRACT Introduction: Fluzone® High-Dose (IIV3-HD) is a trivalent, inactivated, split-virus
influenza vaccine indicated for use in older adults (≥ 65 years of age). It contains 60 µg …

Vaccination against influenza and Streptococcus pneumoniae is recommended for elderly
and immunocompromised individuals. However, there is little information concerning the …

Background Immune responses after influenza immunization are reduced in elderly
individuals, the group at greatest risk for complications and death after influenza. Improved …

Influenza is an important cause of serious illness in very young children with
cardiopulmonary disease. A 4-year study was conducted at two centers to assess …

We investigated, in patients tested between 1991 and 2004, the patterns of mutually
exclusive human immunodeficiency virus-1 thymidine-analogue mutations (TAMS) in 4039 …

A comparative analysis of antibody and cell-mediated immune responses was performed in
ambulatory medically stable elderly and young adults who received the standard-dose of …

Abstract The dose effect (0, 10, 20 and 60 μg) of influenza subunit vaccine on the antibody
response was investigated in nursing-home residents and young controls. The vaccine …

The reactogenicity and immunogenicity of purified influenza virus hemagglutinin (HA)
vaccines administered intramuscularly were evaluated in two placebo-controlled clinical …

The immune response and serum nutritional status of 153 elderly residents of nursing
homes (mean age 84.4 years) and 95 health care workers (mean age 36.8 years) were …