Discogenic back pain: literature review of definition, diagnosis, and treatment
K Fujii, M Yamazaki, JD Kang… - Journal of Bone and …, 2019 - academic.oup.com
Discogenic back pain is multifactorial; hence, physicians often struggle to identify the
underlying source of the pain. As a result, discogenic back pain is often hard to treat—even …
underlying source of the pain. As a result, discogenic back pain is often hard to treat—even …
Critical aspects and challenges for intervertebral disc repair and regeneration—Harnessing advances in tissue engineering
Low back pain represents the highest burden of musculoskeletal diseases worldwide and
intervertebral disc degeneration is frequently associated with this painful condition. Even …
intervertebral disc degeneration is frequently associated with this painful condition. Even …
Multifunctional Nanofibrous Scaffolds with Angle‐Ply Microstructure and Co‐Delivery Capacity Promote Partial Repair and Total Replacement of Intervertebral Disc
F Han, Q Yu, G Chu, J Li, Z Zhu, Z Tu… - Advanced …, 2022 - Wiley Online Library
There is an urgent clinical need for the treatment of annulus fibrosus (AF) impairment
caused by intervertebral disc (IVD) degeneration or surgical injury. Although repairing …
caused by intervertebral disc (IVD) degeneration or surgical injury. Although repairing …
Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc
Tissue engineering holds great promise for the treatment of advanced intervertebral disc
degeneration. However, assessment of in vivo integration and mechanical function of tissue …
degeneration. However, assessment of in vivo integration and mechanical function of tissue …
[HTML][HTML] Intervertebral disc degeneration and regeneration: a motion segment perspective
Back and neck pain have become a primary cause of disability and healthcare spending
globally. While the causes of back pain are multifactorial, intervertebral disc degeneration is …
globally. While the causes of back pain are multifactorial, intervertebral disc degeneration is …
Total disc replacement devices: structure, material, fabrication, and properties
The intervertebral disc (IVD) is an important component of the human spine that maintains
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
Intervertebral disc swelling maintains strain homeostasis throughout the annulus fibrosus: a finite element analysis of healthy and degenerated discs
B Yang, GD O'Connell - Acta biomaterialia, 2019 - Elsevier
Tissues in the intervertebral disc have a large capacity to absorb water, partially due to the
high glycosaminoglycan (GAG) content, which decreases linearly from the nucleus pulposus …
high glycosaminoglycan (GAG) content, which decreases linearly from the nucleus pulposus …
Cartilaginous endplates: a comprehensive review on a neglected structure in intervertebral disc research
KB Crump, A Alminnawi, P Bermudez‐Lekerika… - JOR …, 2023 - Wiley Online Library
The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD)
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …
Customised multiphasic nucleus/annulus scaffold for intervertebral disc repair/regeneration
Background: In the case of a degenerated intervertebral disc (IVD), even though spinal
fusion has provided good short-term clinical results, an alteration of the spine stability has …
fusion has provided good short-term clinical results, an alteration of the spine stability has …
Lessons to be learned and future directions for intervertebral disc biomaterials
Biomaterials science has achieved significant advancements for the replacement, repair and
regeneration of intervertebral disc tissues. However, the translation of this research to the …
regeneration of intervertebral disc tissues. However, the translation of this research to the …