Boron-homologation reactions represent an efficient and programmable approach to
prepare alkylboronates, which are valuable and versatile synthetic intermediates. The …

We report the Sonogashira cross-coupling of aryl ammonium salts catalyzed by air-and
moisture-stable [Pd (NHC)(3-CF3-An) Cl2](An= aniline). This highly active Pd (II)–NHC …

Trifluoromethylated aziridines are the smallest fluorinated N-heterocycle and represent
important strategic building blocks with broad application in drug discovery for the synthesis …

The Matteson-type reactions have received increasing interest in constructing complex
organic molecules via iterative synthetic strategies; however, the current tactics are almost …

The review focuses on recent advances in the methodologies for the formation or
introduction of the CH2F moiety in N-heterocyclic substrates over the past 5 years. The …

We report the first Suzuki–Miyaura cross-coupling of 2-pyridyl ammonium salts by highly
selective N–C activation catalyzed by air-and moisture-stable Pd (II)–NHC (NHC= N …

The ubiquitin-proteasome pathway (UPP) is the major proteolytic system in the cytosol and
nucleus of all eukaryotic cells. The role of proteasome inhibitors (PIs) as critical agents for …

A carbene bearing two geminal boryl substituents, called diborylcarbene (DBC), has been
predicted to be highly Lewis acidic in sharp contrast to the well-studied persistent carbenes …

The direct trifluoromethylthiolation of aziridines with AgSCF3 and iodides is reported. The β-
trifluoromethylthiolated isothiocyanates and amines were selectively obtained by the …

2-Alkylpyridines are a privileged scaffold throughout the realm of organic synthesis and play
a key role in natural products, pharmaceuticals, and agrochemicals. Herein, we report the …